Search Results for: metastatic squamous-cell carcinoma

Extensive regression in pigmented skin lesions: a dangerous confounding feature

Extensive regression in pigmented skin lesions: a dangerous confounding feature

…entation The fully regressed melanoma in Figure 1 was found on the arm of a 50-year-old man, who was recently diagnosed with metastatic melanoma of the ipsilateral axillary lymph nodes (Figure 1A). Dermoscopic examination revealed a diffuse…

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update

…opathologic study of 27 cases. Cancer 1960;13:612-25. 5. Smith KJ, Barrett TL, Skelton HG 3rd, Lupton GP, Graham JH. Spindle cell and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus). Am J Surg Pathol 1989;13:931-39. 6….

Differential Diagnosis in Dermatopathology

Seborrheic keratosis, acanthotic type vs. Eccrine poroma

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…racterized by the presence of fibrin in the wall and/or thrombi in the lumen in the context of an infiltrate of inflammatory cells. In the vast majority of instances, the cells are neutrophils, e.g., in leukocytoclastic vasculitis, septic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Spongiform Pustular Diseases?

…y he thought that is baffling. In a spongiform pustule, neutrophils in variable number are sprinkled among keratocytes whose cell membranes form a lattice. Depending on the stage in migration of neutrophils from the dermis through the epidermis, a…

Nab-paclitaxel-associated photosensitivity: report in a woman with non-small lung cancer and review of taxane-related photodermatoses

Nab-paclitaxel-associated photosensitivity: report in a woman with non-small lung cancer and review of taxane-related photodermatoses

…erapy [7]. Paclitaxel-induced erythema multiforme on sun-exposed skin has previously been observed. A 40-year-old woman with metastatic breast cancer presented with photodistributed erythema multiforme and onycholysis following treatment with…

Dermoscopic clues to diagnose acantholytic dyskeratosis

Dermoscopic clues to diagnose acantholytic dyskeratosis

…nied by several dermatologic adverse events [1]. These include both benign and malignant lesions, such as cutaneous squamouscell carcinoma, verrucal keratosis, plantar hyperkeratosis, hair follicle changes, panniculitis, and photosensitivity [2],…

A quiz from Manaus, Brazil

A quiz from Manaus, Brazil

…h CD34 are also seen [12]. Solitary fibrous tumor (SFT) of the skin is a very uncommon lesion consisting of alternating hypercellular and hypocellular areas of bland spindle cells, arranged in a combination of fascicular, storiform and…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…h Dermatol 1985;121:1442–44. “Granulomas of the sarcoid type with numerous foreign body and Langhans’ giant cells were the dominating features [of metastatic Crohn’s disease]. In accordance with previous results, we found…

Glomangiosarcoma in the shoulder of a 51-year-old man

Glomangiosarcoma in the shoulder of a 51-year-old man

…Shave biopsy showed a cellular neoplasm with a multinodular growth pattern in the dermis (Figure 1A). The neoplasm was very cellular and consisted of round, ovoid and spindle cells with moderate nuclear atypia and frequent mitotic figures (up to 6…