Dermatology Practical & Conceptual

Glomangiosarcoma in the shoulder of a 51-year-old man

…s performed. Histopathological findings Shave biopsy showed a cellular neoplasm with a multinodular growth pattern in the dermis (Figure 1A). The neoplasm was very cellular and consisted of round, ovoid and spindle cells with moderate nuclear atypia…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…oid type with numerous foreign body and Langhans’ giant cells were the dominating features [of metastatic Crohn’s disease]. In accordance with previous results, we found vascular involvement in 2 cases, manifested as granulomatous perivas…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…as well as in the upper part of the dermis Perivascular mixed-cell infiltrate of lymphocytes and neutrophils Patchy infiltrates of neutrophils in lobules in the subcutaneous fat and dispersed also among collagen bundles in the lower part of the retic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

…micron, will ensure cure, i.e., the person will never die of metastatic melanoma. If, however, a melanoma, no matter how thin, already has metastasized by the time the neoplasm is excised in toto, the patient is likely doomed to die of metastatic me…

Differential Diagnosis in Dermatopathology

Discussions

…hologic develop in them. Those range from formation of “squamous eddies” to development of nuclear abnormalities that may simulate vaguely the kind seen in squamous-cell carcinoma. Of the three major patterns of seborrheic keratoses, name…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

…ebaceous gland marks the site where lipid-producing glandular cells of sebaceous lobules meet stratified squamous epithelium of an infundibulum. A sebaceous duct is lined by a thin cornifying squamous epithelium with a barely detectable granular zone…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

…rmatological types, characterized by nonpruriginous erythmato-squamous spots, extremely persistent and rebellious to all treatment. It is exclusively the objective appearance of these dermatoses which led to their mutual approximation to psoriasis. T…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…e perivascular and periadnexal infiltrate with numerous giant cells in the “subpapillary portion of the corium.” The infiltrate also was situated in dermal papillae, around eccrine glands, and in adipose tissue. The extensions of follicul…