Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine, Apocrine, and Apoeccrine Sweat Glands?

“Evidence is presented that in adult human axillae there exists a third type of sweat gland tentatively designated as the apoeccrine sweat gland. This type of gland shows a segmental or diffuse apocrinelike dilatation of its secretory tubule…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

“Widths of excision as much as 100 mm from the edge of the lesion have been advocated and most surgeons have practiced wide excision with a 50-mm margin area without anatomical limitations.” McLeod GRC. Malignant melanoma: primary trea…

Dermatology Practical & Conceptual

Papillary adenocarcinoma in situ of the skin: report of four cases

Abstract Although rare isolated cases of adenocarcinoma in situ of skin have been reported in the literature, adenocarcinoma in situ of skin as a concept and as a diagnostic category has not been established in the field of dermatopathology. In this…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

“. . . We conclude that dermatofibromas can very rarely metastasize. Risk factors for metastasis may include relatively large size, high cellularity, and local recurrence. It would appear that metastasizing dermatofibromas behave in an indol…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…gnosis histopathologic Other cell-poor subepidermal blistering diseases, such as a suction blister, cell-poor pemphigoid, and one expression of acquired epidermolysis bullosa; all of these “cell poor” blistering diseases may be indistingu…

Histologic Diagnosis of Inflammatory Skin Diseases

Rosacea

Rosacea Synonyms Gutta rosea Presentation stereotypical Age and sex Young and middle-aged adults, usually Caucasian women Distribution of lesions Center of the face in vertical and horizontal directions, i.e., nose, forehead, cheeks, and chin Indivi…

Differential Diagnosis in Dermatopathology

Discussions

…light eruption. Biopsy of the hive-like lesions in those four diseases produces a specimen from which sections of tissue display changes diagnostic of a specific disease, ones very different from findings in urtica. Subtle differences histopathologi…

Differential Diagnosis in Dermatopathology

Urticarial reaction to an arthropod assault vs. Urtica

An inflammatory process caused by superficial fungi, i.e., fungi situated superficially in the cornified layer and in other cornified structures, and expressed clinically as smooth-surfaced papules, scaly papules, scaly plaques, nodules, pustules, v…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…en or young adults as deep-situated nodules, especially on the hands and buttocks, and in the pretibial region. Perforating granuloma annulare presents itself usually on the dorsa of hands as tiny umbilicated papules topped by crusts. Widespread gran…

Histologic Diagnosis of Inflammatory Skin Diseases

Acne vulgaris

Synonyms Acne simplex Presentation stereotypical Age and sex Adolescents of both sexes; usually more severe in males. May affect neonates. Distribution of lesions Regions in which large sebaceous units are joined to vellus follicles, i.e., the face,…