Histologic Diagnosis of Inflammatory Skin Diseases

Erysipelas

…ilection for older persons with diabetes, peripheral vascular disease, and abuse of alcohol Distribution of lesions Face and lower extremities especially Individual lesions Erythematous edematous patch or plaque with pseudopods at the periphery, topp…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

…ithelial adnexa are folliculo-sebaceous-apocrine units on one hand and eccrine units on the other; the nonepithelial adnexa are smooth muscles, nerves, and blood vessels. Each of those normal adnexal structures has its own distinctive histologic attr…

Histologic Diagnosis of Inflammatory Skin Diseases

Measles

…Bibliography Bibliography for viral exanthems Alsop J, et al. Hand-foot-mouth disease in Birmingham. Br Med J 1959;2:1708. Barnadas MA, Alegre M, Baselga E, Randazzo L, Margall N, et al. Histopathological changes of primary HIV infection: description…

Dermatology Practical & Conceptual

Papillary adenocarcinoma in situ of the skin: report of four cases

…excised with a positive margin, and there was no evidence of disease progression at the six-year follow-up. The photomicrographs of H&E and P63 stain provided by the authors for their case (figures 2 and 3 in the article) showed clearly the pres…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

…uni et al. told of a patient with a lesion on the dorsum of a foot less than 1.5 centimeters in diameter, which was diagnosed by conventional microscopy as “fibrous histiocytoma.” The lesion recurred at the local site three times first wi…

Histologic Diagnosis of Inflammatory Skin Diseases

Rosacea

…ocular dermatitis consists of papules and pustules around the mouth and eyes of young women especially. Blepharitis occurs episodically and may be followed by conjunctivitis and keratitis. Lupus miliaris disseminatus faciei is a papular variant of gr…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…tissue, C-shaped plaques that sweep around the angles of the mouth, extracutaneous involvement common, often lethal in the first months of life; a number of subtypes are differentiated from one another on the basis of features clinical. Pyloric atre…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…n or young adults as deep-situated nodules, especially on the hands and buttocks, and in the pretibial region. Perforating granuloma annulare presents itself usually on the dorsa of hands as tiny umbilicated papules topped by crusts. Widespread granu…

Differential Diagnosis in Dermatopathology

Discussions

…light eruption. Biopsy of the hive-like lesions in those four diseases produces a specimen from which sections of tissue display changes diagnostic of a specific disease, ones very different from findings in urtica. Subtle differences histopathologic…