Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

…lupus erythematosus by definition is systemic, it is redundant to designate it anything other than “lupus erythematosus,” analogous to melanoma (not malignant melanoma) and lymphoma (not malignant lymphoma). Just as lupus erythematosus af…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…an abscess previously contained a hair shaft, which indicates that the process began as a suppurative infundibulitis. The linear arrangement in orientation vertically of the abscesses in the dermis and the subcutaneous fat reflects the course of an…

Histologic Diagnosis of Inflammatory Skin Diseases

Paraneoplastic pemphigus

…patches, or papules; rarely vesicles; oral erosions secondary to vesiculation Course Variable, but often persisting as long as the underlying neoplastic process goes unchecked Variations clinical Lymphoma or leukemia often is severe and results in…

Dermatology Practical & Conceptual

A reticulated pigmented rash on the lower leg

…sed by sleeping on hot bricks) and kengri cancer (seen only in the Kashmir region of India and caused by wearing a heater pot under the clothes). Cases of Merkel cell carcinoma and marginal zone lymphoma have also been described with these lesions [7…

Differential Diagnosis in Dermatopathology

Discussions

…of some large lymphocytes, extravasated erythrocytes, edema of the papillary dermis, dilated venules and capillaries, cells of the infiltrate present sometimes in the upper part of the subcutaneous fat, spongiosis and spongiotic vesiculation, epiderm…

Differential Diagnosis in Dermatopathology

Discussions

…ists. Photoallergic dermatitis and phototoxic dermatitis share the following attributes histopathologic: perivascular infiltrates that involve at least the vessels of the superficial plexus, infiltrates of mixed inflammatory cells, erythrocytes extra…

Differential Diagnosis in Dermatopathology

Photoallergic dermatitis vs. Phototoxic dermatitis

A systemic lymphoma of T-lymphocytes that manifests itself first in the skin as macules and then patches that often are scaly. Most people with the disease have only scaly macules and patches for a lifetime, but some patients may develop papules, pl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

…ous VZV vasculitis without epidermal involvement is presented. The patient received chemotherapy for a large B cell lymphoma. He presented a few painless papules on one hand and in the axilla. A lymphocytic vasculitis was evidenced.” Uhoda I,…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

…Correlation clinicopathologic Papules, plaques, nodules, and tumors are formed of dense nodular mixed-cell infiltrates in the reticular dermis and, sometimes, in the upper part of the subcutaneous fat. The dusky hue is due to prominent dilation of…