Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…erences between them histopathologically, namely, inflammatory cells around follicles and irregular epidermal growth in the former, and inflammatory cells only in dermal papillae with partial atrophy of the epidermis in the latter. In the same articl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo?

…n of the rete pegs and melanocytic hyperplasia confined to the basal cell layer.” Farmer ER, Hood AF. Melanocytic tumors. In: Farmer ER, Hood AF, eds. Pathology of the Skin. New York, NY: McGraw-Hill, 2000:1108. “Solar lentigo shows elo…

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

…eratinizing tumors including seborrheic keratosis and squamous cell carcinoma or in tumors with sebaceous differentiation, but also in juvenile xanthogranuloma or granulomatous skin diseases [1]. It is more surprising that recent dermatoscopic observ…

Differential Diagnosis in Dermatopathology

Discussions

…osis, a thickened epithelium, and an infiltrate of mononuclear cells. The white color (leuko-) in both leukokeratosis and leukoplakia results from abnormal production and maceration of cornified cells. But the essential character of the two condition…

Differential Diagnosis in Dermatopathology

Guttate psoriasis vs. Guttate (dermatosis) parapsoriasis

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

…54 A&B. Signs indicative of the cause of chondrodermatitis nodularis helicis: external trauma. What is called chondrodermatitis nodularis helicis simply is a response to injury by pressure sustained on a helix, the result being ulceration and gra…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.63.1A: Perivascular dermatitis, interface, vacuolar + 10.63.1B: Smudged appearance of the dermoepidermal junction, focally thinned epidermis, and plentiful mucin throughout the dermis = Lupus erythematosus, discoid ┬áThe presence…

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…liam Montagna, Ph.D.) Unmyelinated axons surrounded by Schwann cells are arrayed in a branching and overlapping network. Many of the unmyelinated axons terminate near the dermoepidermal junction, where basal lamina of their Schwann cells make contact…