Spotlight on “Rosacea”

Living with Rosacea

Rosacea has significant impact on quality of life, an observation that has been validated by a number of qualitative and quantitative studies using disease severity instruments such as the Dermatology Life Quality Index (DLQI) and Willingness-to-pa…

Differential Diagnosis in Dermatopathology

Discussions

Nevus verrucosus and acanthosis nigricans are processes that affect the papillary dermis and the epidermis. Both conditions may display hyperkeratosis, epidermal hyperpigmentation, papillomatosis, melanophages, and an increased number of fibrocytes…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

An inflammatory process that tends to involve mucous membranes, as well as skin, and of the latter the acra especially. The stereotypical presentation is lesions composed of concentric rings (“iris” and “target” type). The co…

Histologic Diagnosis of Inflammatory Skin Diseases

Atheroemboli

Atheroemboli Presentation stereotypical Age and sex Elderly persons, especially those with atherosclerosis Distribution of lesions Localized to lower extremities Individual lesions Purpuric macules, including splinter hemorrhages, livedo reticularis…

Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

…boy SJ. Disseminated intravascular coagulation: a dermatologic disease. Int J Dermatol 1977;16:47–51. McKay DG. Disseminated Intravascular Coagulation: An Intermediary Mechanism of Disease. New York: Harper & Row, 1965. Ontachi Y, Asakura H, Funa…

Differential Diagnosis in Dermatopathology

Discussions

…fatal; morphea never is. Scleredema (known also as scleredema adultorum of Buschke) affects young adults. About 50 percent of patients present themselves to a physician at an age younger than 20 years. There is no predilection for sex. The changes a…

Differential Diagnosis in Dermatopathology

Discussions

Pruritic urticarial papules and plaques of pregnancy (PUPPP) and a superficial response to an assault by an arthropod are inflammatory diseases that share many features clinical and findings histopathologic. When viewed through a conventional micros…

Differential Diagnosis in Dermatopathology

Discussions

…es acuta and pityriasis lichenoides chronica are not different diseases, but different names for changes morphologic of the same disease. Pityriasis lichenoides acuta and pityriasis lichenoides chronica have many findings histopathologic in common: m…

Differential Diagnosis in Dermatopathology

Urticaria vs. Urticarial lesions of bullous pemphigoid

An inflammatory process that tends to involve mucous membranes, as well as skin, and of the latter the acra especially. The stereotypical presentation is lesions composed of concentric rings (“iris” and “target” type). The co…