Search Results for: still disease, adult-onset

Dermatology Practical & Conceptual

Pre-emptive diagnosis of a case of scabies by dermatopathology

…. A typical infestation involves a stable population of 15-20 adult female mites, which burrow in the stratum corneum where they deposit eggs and faeces [2]. The clinical symptoms of an intensely itchy eruption occur typically after a delay of two to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…response to superficial trauma; however, a form appearing in adult years exists and is associated with diabetes and chronic renal disease. Autosomal recessive, dominant, sporadic, and acquired forms have been described. The papules overly a focus of…

Histologic Diagnosis of Inflammatory Skin Diseases

Pityriasis rubra pilaris

…yms Pityriasis pilaris Presentation stereotypical Age and sex Adults in about the fifth decade of life and children in the first 5 years of life; same frequency in both sexes Distribution of lesions Symmetric and widespread Arrangement of lesions Pap…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Precursor Lesions of Melanoma?

…kin. In addition, these lesions continue to appear throughout adult life, even into the sixth and seventh decades. The histologic picture of atypical melanocytic hyperplasia, dense dermal lymphocytic infiltration with fibroplasias, and new blood vess…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Scleroderma?

…et al.. Localized scleroderma in childhood is not just a skin disease. Arthritis Rheum 2005;52(9):2873-81. “The pathogenesis of systemic sclerosis (SSc; scleroderma) is still enigmatic.” Feghali-Bostwick CA. Genetics and proteomics in scl…

Dermatology Practical & Conceptual

Multiple confluent reddish nodules

…yright: ©2013 Jeunon et al.] Answer Lobomycosis (Jorge Lobo’s disease) Discussion Lobomycosis is a chronic infectious granulomatous disease of the dermis and hypodermis caused by the fungus Lacazia loboi [1,2]. There is no involvement of internal org…

Differential Diagnosis in Dermatopathology

Pityriasis lichenoides acuta vs. Pityriasis lichenoides chronica

An inflammatory process caused by the acarus Sarcoptes scabiei and consisting of papules, papulovesicles, papulopustules, and vesicles, some arranged in linear or curvilinear tracks (burrows). Sometimes nodules are present, especially in the interdi…

Differential Diagnosis in Dermatopathology

Discussions

…focal acantholytic dyskeratosis (which is like Darier’s disease histopathologically, but not clinically or biologically), cornoid lamellation (which usually is taken to be a histopathologic sign of porokeratosis), and seborrheic keratosis-like…