Differential Diagnosis in Dermatopathology

Discussions

Nevus verrucosus and acanthosis nigricans are processes that affect the papillary dermis and the epidermis. Both conditions may display hyperkeratosis, epidermal hyperpigmentation, papillomatosis, melanophages, and an increased number of fibrocytes…

Living with Rosacea

Living with Rosacea

Rosacea has significant impact on quality of life, an observation that has been validated by a number of qualitative and quantitative studies using disease severity instruments such as the Dermatology Life Quality Index (DLQI) and Willingness-to-pa…

Erythema in Rosacea

Erythema in Rosacea

Current treatment of erythema in rosacea This type has traditionally been treated with avoidance of flushing, photoprotection, and surgical strategies including electrosurgery or laser therapies to treat the erythema and telangiectasias.  Laser the…

Histologic Diagnosis of Inflammatory Skin Diseases

Gas gangrene

Gas gangrene Synonyms Clostridial myonecrosis Presentation stereotypical Age and sex Usually adults of both sexes Distribution of lesions Localized to sites of deep wounds Individual lesions Dusky erythematous plaques and hemorrhagic bullae through…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema annulare centrifugum

…of lupus erythematosus and dermatomyositis, and the deficiency diseases, acrodermatitis enteropathica, necrolytic migratory erythema, pellagra, kwashiorkor, Hartnup’s disease, and maple syrup disease, to mention but a few examples of diseases t…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

A condition of persons of any age, but particularly children with a genetic proclivity for allergic rhinitis and conjunctivitis, and allergic asthma. Intense pruritus induces patients to rub the skin intensely and to scratch furiously, the resultant…

Histologic Diagnosis of Inflammatory Skin Diseases

Atheroemboli

Atheroemboli Presentation stereotypical Age and sex Elderly persons, especially those with atherosclerosis Distribution of lesions Localized to lower extremities Individual lesions Purpuric macules, including splinter hemorrhages, livedo reticularis…

Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

…boy SJ. Disseminated intravascular coagulation: a dermatologic disease. Int J Dermatol 1977;16:47–51. McKay DG. Disseminated Intravascular Coagulation: An Intermediary Mechanism of Disease. New York: Harper & Row, 1965. Ontachi Y, Asakura H, Funa…

Differential Diagnosis in Dermatopathology

Urticaria vs. Urticarial lesions of bullous pemphigoid

A condition of persons of any age, but particularly children with a genetic proclivity for allergic rhinitis and conjunctivitis, and allergic asthma. Intense pruritus induces patients to rub the skin intensely and to scratch furiously, the resultant…