Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen planus-like keratosis Solar keratosis with lichenoid infiltrate of lymphocytes 1. Crusts often 1. No crusts in non-traumatized lesions 2. Ortho- and parakeratosis not arranged in discrete columns 2. Ortho- and parakeratosis alternate wi…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen simplex chronicus Hypertrophic lichen planus 1. Granular zone thickened, but not with periodicity and in wedge shape 1. Granular zone often thickened focally at nearly periodic intervals and in wedge shape, especially in infundibula 2….

Differential Diagnosis in Dermatopathology

Discussions

…type of superficial squamous-cell carcinoma, designated solar keratosis. Clinically, pale-cell acanthoma usually develops on a leg of women as an orange to pink papule or small plaque covered by wafer-like scales. A typical lesion has a sticky surfac…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Regression of lichen planus-like keratosis Regression of primary cutaneous melanoma 1. Signs of residual solar lentigo or reticulated seborrheic keratosis apparent in sections of tissue sometimes 1. No residual keratocytic neoplasm such as solar…

Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

Papules, nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

…ing of infundibula may be seen in inflammatory diseases as unalike as lichen planopilaris and discoid lupus erythematosus on one hand and noninflammatory conditions such as keratosis pilaris and phrynoderma on the other. The infiltrates of lymphocyte…

Histologic Diagnosis of Inflammatory Skin Diseases

See Classification of Pigmented Lesions

…artomas Collagenous nevus, papillary dermal type Nevoid hyperkeratosis of the nipple Benign neoplasms Solar lentigo, including lichen planus-like keratosis Seborrheic keratosis Malignant neoplasms Basal cell carcinoma, pigmented Solar keratosi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Focus of Infection?

…se considered in some relation with neuropathy:            1, lichen planus; 2, lichen simplex (Vidal); 3, herpes simplex; 4, herpes zoster; 5, eczema (neurotic); 6, alopecia areata; 7, dermatitis herpetiformis; 8, scleroderma; 9, vitiligo. Group 3:…