Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

…rnity of “vertical growth phase,” or where a solar keratosis ends and a squamous-cell carcinoma begins; solar keratosis is a superficial squamous-cell carcinoma. These exercises not only are futile, but they also deter histopathologists f…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Parapsoriasis?

…parapsoriasis- Variant: digitate dermatosis      3. Pityriasis lichenoides           a. Pityriasis lichenoides et varioliformis acuta (Mucha-Habermann)           b. Pityriasis lichenoides chronica (Juliusberg)           c. Lymphomatoid papulosis Woo…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen simplex chronicus Hypertrophic lichen planus 1. Granular zone thickened, but not with periodicity and in wedge shape 1. Granular zone often thickened focally at nearly periodic intervals and in wedge shape, especially in infundibula 2….

Differential Diagnosis in Dermatopathology

Discussions

…r) mucinosis. When pale-cell acanthosis occurs in a seborrheic keratosis, for example, the lesion may simulate pale-cell acanthoma closely, but the seborrheic keratosis may be recognized for what it is by the presence of laminated hyperkeratosis, tun…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Regression of lichen planus-like keratosis Regression of primary cutaneous melanoma 1. Signs of residual solar lentigo or reticulated seborrheic keratosis apparent in sections of tissue sometimes 1. No residual keratocytic neoplasm such as solar…

Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

Papules, nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

…ythematosus on one hand and noninflammatory conditions such as keratosis pilaris and phrynoderma on the other. The infiltrates of lymphocytes and the changes in surface epidermis eliminate lichen planus and discoid lupus erythematosus from being conf…

Histologic Diagnosis of Inflammatory Skin Diseases

See Classification of Pigmented Lesions

…sis of the nipple Benign neoplasms Solar lentigo, including lichen planus-like keratosis Seborrheic keratosis Malignant neoplasms Basal cell carcinoma, pigmented Solar keratosis, pigmented Melanocytic lesions Benign Melanosis Simple lenti…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Focus of Infection?

…ose considered in some relation with neuropathy:            1, lichen planus; 2, lichen simplex (Vidal); 3, herpes simplex; 4, herpes zoster; 5, eczema (neurotic); 6, alopecia areata; 7, dermatitis herpetiformis; 8, scleroderma; 9, vitiligo. Group 3:…