Search Results for: nodular basal-cell carcinoma

Histologic Diagnosis of Inflammatory Skin Diseases

Epidermolysis bullosa simplex

…y developed Dermal papillae preserved beneath what seems, at first blush, to be a subepidermal blister Vacuoles in epidermal basal cells at the sides of the blister Clefts cut a swath through epidermal basal cells Little or no infiltrate of…

Melanoma arising in a giant nevus spilus maculosus

Melanoma arising in a giant nevus spilus maculosus

…unch biopsy of the speckled lentiginous nevus. The biopsy was taken from the thigh. Mild acanthosis and hyperpigmentation of basal keratinocytes is present but there is no marked proliferation of melanocytes. Figures 6A-G. Histopathology of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…est, which gives rise to dorsal root and sympathetic ganglia, and to their nerve processes, Schwann cells, endoneural sheath cells, and laminar cells of specialized sensory end organs. Nerves in the reticular dermis travel along the course of the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Acquired Epidermolysis Bullosa?

…: 1. The finding of IgG at the BMZ by direct immunofluorescence microscopy 2. Demonstration of blister formation beneath the basal lamina, which remains on the epidermal side of the blister by electron microscopy 3. Deposition of IgG in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Rosacea

…onships among the different expressions of rosacea, for example, how the telangiectatic form of it is related to papular and nodular manifestations. The link between the papular and nodular manifestations also is not clear. Some papular lesions are…

Differential Diagnosis in Dermatopathology

Erythroderma of psoriasis vs. Erythroderma of mycosis fungoides

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

…light. (See quandary titled “Lentigo maligna melanoma, superficial spreading melanoma, acral lentiginous melanoma, and nodular melanoma). The term lentigo maligna is emblematic of all too many misnomers in dermatology, pathology, and…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…t forth as follows: Superficial perivascular dermatitis (Fig. 5.6A) Superficial and deep perivascular dermatitis (Fig. 5.6B) Nodular and diffuse dermatitis (Fig. 5.6C) Vasculitis (Fig. 5.6D) Intraepidermal vesicular and pustular dermatitis (Fig….