Differential Diagnosis in Dermatopathology

Erythroderma of psoriasis vs. Erythroderma of mycosis fungoides

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

…roliferation of small blood vessels lined by plump endothelial cells throughout the dermis Correlation clinicopathologic The nodules and tumors are constituted of dense nodular and diffuse infiltrates of lymphocytes, some of them in lymphoid follicl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

“Melanoma arising from lentigo maligna is preceded by or forms a part of a recognizable series of events affecting the melanocytic cellular system in a way similar to these stages. First, there is a long period characterized by an increase in…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…sis morphologically of the (1) patterns formed by inflammatory cells, sometimes in conjunction with changes in epidermal and adnexal epithelium, and the (2) character of the inflammatory cells themselves. Although algorithms were utilized in the appl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

“Epidermoid cyst. Synonym: Sebaceous cyst, steatoma, epithelial cyst. Definition: A cyst containing keratin and its breakdown products, surrounded by an epidermoid wall.” Mackie RM. Epidermal skin tumors. In: Champion RH, Burton JL, Eb…