Differential Diagnosis in Dermatopathology

Discussions

Pruritic urticarial papules and plaques of pregnancy (PUPPP) and a superficial response to an assault by an arthropod are inflammatory diseases that share many features clinical and findings histopathologic. When viewed through a conventional micros…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema annulare centrifugum

…of lupus erythematosus and dermatomyositis, and the deficiency diseases, acrodermatitis enteropathica, necrolytic migratory erythema, pellagra, kwashiorkor, Hartnup’s disease, and maple syrup disease, to mention but a few examples of diseases t…

Differential Diagnosis in Dermatopathology

Trichoadenoma vs. Microcystic adnexal carcinoma

An inflammatory process that tends to involve mucous membranes, as well as skin, and of the latter the acra especially. The stereotypical presentation is lesions composed of concentric rings (“iris” and “target” type). The co…

Dermatology Practical & Conceptual

Widespread pruritic papules on the trunk and extremities

The patient A 42-year-old Caucasian man presented with a 15-year history of a widespread, persistent, pruritic eruption over his trunk and extremities. He was not on medication and had no relevant family history. On physical examination, multiple di…

Histologic Diagnosis of Inflammatory Skin Diseases

Parasitic infestations

…zil. Int J Dermatol 2004 Jul;43(7):511-15. Kaposi M. Parasitic diseases of the skin, dermatoses parasitaire. In: Hebra F, Kaposi M. On Diseases of the Skin Including the Exanthemata. London: New Sydenham Society, 1880: 5. Magana M, Messina M, Bustama…

Histologic Diagnosis of Inflammatory Skin Diseases

Acquired epidermolysis bullosa

…idermolysis bullosa acquisita. In: Jordon RE. Atlas of Bullous Disease. New York: Churchill Livingstone, 2000;125–38. Wise F, Lautman MF. Epidermolysis bullosa beginning in adult life. The acquired form of the disease, with report of a case and revie…

Histologic Diagnosis of Inflammatory Skin Diseases

Eosinophilic folliculitis

…Infants of both sexes, restricted usually to the scalp; young adults, especially males, infected by HIV (eosinophilic pustular folliculitis of HIV), and some Japanese and Caucasians with no infection by HIV (Ofuji’s disease) Distribution of le…

Differential Diagnosis in Dermatopathology

Discussions

Features clinical common to amputation neuroma secondary to rudimentary supernumerary digit and acquired digital fibrokeratoma are location, shape, and consistency. Both conditions occur on or near fingers and both are firm, keratotic, polypoid proj…