Differential Diagnosis in Dermatopathology

Discussions

…oma is a solitary excrescence that arises from the skin of an adult near an interphalangeal joint of a finger. The projection may be elongated (polypoid) or domed (sessile), but always is keratotic. Other fibromas that have attributes histopathologic…

Histologic Diagnosis of Inflammatory Skin Diseases

Acquired epidermolysis bullosa

…being reported on in children, as well as in adolescents and adults, all of whom are afflicted by a variety of diseases autoimmune and systemic of different kinds (e.g., inflammatory bowel diseases, lupus erythematosus, systemic amyloidosis, thyroid…

Histologic Diagnosis of Inflammatory Skin Diseases

Eosinophilic folliculitis

…Infants of both sexes, restricted usually to the scalp; young adults, especially males, infected by HIV (eosinophilic pustular folliculitis of HIV), and some Japanese and Caucasians with no infection by HIV (Ofuji’s disease) Distribution of les…

Differential Diagnosis in Dermatopathology

Discussions

…h sometimes is referred to imprecisely as the drug-induced or adult form of toxic epidermal necrolysis) because those two conditions have so many features in common. Both diseases are typified clinically by widespread reddish lesions, involvement of…

Differential Diagnosis in Dermatopathology

Trichoadenoma vs. Microcystic adnexal carcinoma

An inflammatory process caused by the acarus Sarcoptes scabiei and consisting of papules, papulovesicles, papulopustules, and vesicles, some arranged in linear or curvilinear tracks (burrows). Sometimes nodules are present, especially in the interdi…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

…f fluids from skin unprotected by an epidermis. Lyell’s disease (toxic epidermal necrolysis) in adults is an expression fulminant of erythema multiforme, akin to Stevens-Johnson syndrome in children. Nikolsky’s sign can be elicited almost…

Differential Diagnosis in Dermatopathology

Discussions

…attributes histopathologic of xanthogranulomas (childhood and adult) and the for reticulohistiocytic granuloma, a student could conclude that the two “granulomas” were separate and distinct from one another. On closer inspection and on re…