Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pernio, Perniosis, Lupus Pernio, Chilblain, and Chilblain Lupus?

…es older persons and men Findings by conventional microscopy Superficial and deep perivascular infiltrates of lymphocytes Superficial and deep perivascular infiltrates of lymphocytes Laboratory investigation Antinuclear antibody positive Antinucl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

“Melanoma arising from lentigo maligna is preceded by or forms a part of a recognizable series of events affecting the melanocytic cellular system in a way similar to these stages. First, there is a long period characterized by an increase in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Toxic Erythema?

“Toxic erythema: Red or pinkish color of the skin, if localized, probably due to external cause; if generalized, frequently of internal origin such as derangement of the gastrointestinal tract; ingestion of drugs or antitoxin.” Knowles…

Histologic Diagnosis of Inflammatory Skin Diseases

Pernio

Pernio Synonyms Dermatitis congelationis Chilblains Chilblain lupus Perniosis Erythema pernio Presentation stereotypical Age and sex Young persons usually with no predilection for either sex Distribution of lesions Fingers, toes, nose, and ears In…

Differential Diagnosis in Dermatopathology

Erythroderma of psoriasis vs. Erythroderma of mycosis fungoides

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidermal Cyst and Epidermoid Cyst?

“Epidermoid cyst. Synonym: Sebaceous cyst, steatoma, epithelial cyst. Definition: A cyst containing keratin and its breakdown products, surrounded by an epidermoid wall.” Mackie RM. Epidermal skin tumors. In: Champion RH, Burton JL, Eb…