Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

…ema multiforme in children, and Lyell catalogued two unrelated diseases under the lone heading of “toxic epidermal necrolysis”; one of those diseases is an analogue in adults of Stevens-Johnson syndrome, i.e., severe widespread erythema m…

Differential Diagnosis in Dermatopathology

Discussions

…ch sometimes is referred to imprecisely as the drug-induced or adult form of toxic epidermal necrolysis) because those two conditions have so many features in common. Both diseases are typified clinically by widespread reddish lesions, involvement of…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen striatus

…ous epidermal nevus is included here as an “inflammatory disease,” even though it truly is a hamartoma, the reason for that liberty being taken because clinically, and histopathologically, it resembles an inflammatory disease, as the firs…

Differential Diagnosis in Dermatopathology

Discussions

At first glance at the two columns preceding, one for attributes histopathologic of xanthogranulomas (childhood and adult) and the for reticulohistiocytic granuloma, a student could conclude that the two “granulomas” were separate and di…

Dermatology Practical & Conceptual

Widespread pruritic papules on the trunk and extremities

The patient A 42-year-old Caucasian man presented with a 15-year history of a widespread, persistent, pruritic eruption over his trunk and extremities. He was not on medication and had no relevant family history. On physical examination, multiple di…