Search Results for: alpha-1 antitrypsin deficiency

Therapeutic Strategies in Dermatology

Viral Exanthems: Treatment

…ric cases,hydroxyzine syrup (dosed at 1-2 mg/kg/day divided 3-4 times daily) or diphenhydramine elixir (6.25 mg for ages 2-5, 12.5-25 mg for ages 6-11, 25-50 mg for ages 12 and older) every 6 to 8 hours or at bedtime can be used. Tepid baths with…

Therapeutic Strategies in Dermatology

Linear IgA Bullous Dermatosis: Key Points

…rations occurs in approximately 30-45% of patients. Oral lesions are frequently located on the palate or buccal mucosa. About 10% of patients have conjunctival involvement (conjunctival injection, discharge, or a gritty sensation) that can lead to…

Therapeutic Strategies in Dermatology

Rosacea: Treatment

…apulo-pustular rosacea). Brimonidine 0.33% gel (for ET rosacea). Metronidazole 0.75 and 1% (gel, cream, lotion). Azelaic acid 15 and 20% (cream). Sulfacetamide 10%-sulfur 5% (gel, cream, topical suspension, wash). Systemic Doxycycline 40 mg capsule…

Therapeutic Strategies in Dermatology

Flushing: Treatment

…ushing rather than nonspecific therapy (see Shelley WB, Shelley ED: Advanced Dermatologic Therapy, WB Saunders, Philadelphia, 1987, p. 196-201, for a list of various drug interactions and therapies). Highly localized, unilateral, or dermatomal…

Therapeutic Strategies in Dermatology

Rosacea: Key Points

…ushing can alleviate rosacea symptoms. Newer topical treatments provide effective options for treating rosacea subtypes. The alpha adrenergic agonist brimonidine (Mirvaso) effectively reduces erythema in erythemato-telangiectactic rosacea, as well…

Therapeutic Strategies in Dermatology

Spider Bites: Key Points

…olve cytotoxic factors or inflammatory mediators resulting in inflammation and necrosis of skin. They are summarized in Table 1. Table 1: Spiders and their toxins Common name Characteristic physical features of the spider Toxins contained in the…

Therapeutic Strategies in Dermatology

Linear IgA Bullous Dermatosis: Treatment

…BD. Oxacillin, dicloxacillin, and erythromycin given at doses of 50 mg per day have been used in childhood LABD. Tetracycline 1000-1500 mg/day plus nicotinamide 500 mg two to three times a day have been used in adults. Tetracyclines should be…

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Initial Evaluation

…platelet count APLS: Anticardiolipin IgA/G/M, beta-2-glycoproteins IgA/G/M, lupus anticoagulant Factor V Leiden Protein C/S deficiency: activated protein C resistance, protein C functional assay, free protein S antigen assay Prothrombin gene…

Therapeutic Strategies in Dermatology

Sarcoidosis: Treatment

…sarcoidosis. The granulomas frequently convert vitamin D from the inactive form (vitamin D 25) to the active form (vitamin D 1,25), and patients may be hypercalcemic as well. When clinicians screen for vitamin D deficiency, they are often only…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Treatment

…systemic immunosuppression and/or the use of multiple therapeutic agents in combination. First steps Oral prednisone 0.75 to 1 mg/kg daily will result in a dramatic clinical response in 24-48 hours. The rapid response to prednisone is almost…