Search Results for: alpha-1 antitrypsin deficiency

Therapeutic Strategies in Dermatology

Porphyria Cutanea Tarda: Overview

…ith erythropoietin. Subsequent steps Phlebotomy is continued until clinical improvement occurs, keeping the hemoglobin in the 10- to 11-g range. Urine porphyrins fall with phlebotomy and may continue to fall for months after phlebotomy is…

Therapeutic Strategies in Dermatology

Spider Bites: Key Points

…olve cytotoxic factors or inflammatory mediators resulting in inflammation and necrosis of skin. They are summarized in Table 1. Table 1: Spiders and their toxins Common name Characteristic physical features of the spider Toxins contained in the…

Therapeutic Strategies in Dermatology

Rosacea: Key Points

…ushing can alleviate rosacea symptoms. Newer topical treatments provide effective options for treating rosacea subtypes. The alpha adrenergic agonist brimonidine (Mirvaso) effectively reduces erythema in erythemato-telangiectactic rosacea, as well…

Therapeutic Strategies in Dermatology

Flushing: Treatment

…ushing rather than nonspecific therapy (see Shelley WB, Shelley ED: Advanced Dermatologic Therapy, WB Saunders, Philadelphia, 1987, p. 196-201, for a list of various drug interactions and therapies). Highly localized, unilateral, or dermatomal…

Therapeutic Strategies in Dermatology

Sarcoidosis: Treatment

…sarcoidosis. The granulomas frequently convert vitamin D from the inactive form (vitamin D 25) to the active form (vitamin D 1,25), and patients may be hypercalcemic as well. When clinicians screen for vitamin D deficiency, they are often only…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Treatment

…systemic immunosuppression and/or the use of multiple therapeutic agents in combination. First steps Oral prednisone 0.75 to 1 mg/kg daily will result in a dramatic clinical response in 24-48 hours. The rapid response to prednisone is almost…

A Clinical Atlas of 101 Common Skin Diseases

Porphyria Cutanea Tarda

A disease manifested chiefly in the skin by vesicles and bullae that appear on sites of trauma, especially the face and dorsa of the hands, often in conjunction with macular hyperpigmentation and hypertrichosis of a face and sclerodermoid changes…

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp. A papule of it tends to become a plaque, a nodule, a…