Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/lymphoma

Malignant neoplasms of B-lymphocytes especially that present themselves usually as papules, nodules, and tumors, sometimes solitary but at other times numerous, and often in clusters on any anatomic site. When "primary," B-cell lymphomas o…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Key Points

…or anti-phospholipid antibody syndrome. Lesions of pernio have been reported in patients with chronic myelomonocytic leukemia, and patients with extensive or atypical cutaneous lesions, cellular atypia on histology, or suggestive systemic symptoms wa…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Treatment

…warm, and keeping them warm. Wet, constrictive clothing should be removed immediately. The affected skin should be kept warm and dry, with loose, layered clothing, and the subject should stay in a warm environment. The best way to maintain distal ext…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

Malignant neoplasms of B-lymphocytes especially that present themselves usually as papules, nodules, and tumors, sometimes solitary but at other times numerous, and often in clusters on any anatomic site. When "primary," B-cell lymphomas o…

A Clinical Atlas of 101 Common Skin Diseases

Sweet’s Syndrome

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…

Therapeutic Strategies in Dermatology

Mucha-Habermann Disease: Overview

…is Acuta / Pityriasis Lichenoides Chronica This condition is a benign and often self-limited lymphocytic vasculitis. Pityriasis lichenoides chronica (PLC) is treated like pityriasis lichenoides et varioliformis acuta (PLEVA). A rare variant of PLEVA,…

Therapeutic Strategies in Dermatology

Lupus: Key Points

…emic lupus erythematosus. The diagnosis of cutaneous lupus may be confirmed by skin biopsy, which in general reveals a vacuolar interface dermatitis, often in association with a lymphocytic infiltrate with plasma cells, epidermal atrophy, and mucin….

A Clinical Atlas of 101 Common Skin Diseases

Pyoderma Gangrenosum

An inflammatory process that often begins as a suppurative folliculitis manifested clinically as pustules. It rapidly extends to become ulcers marked at their periphery by boggy tissue. The skin disease is associated commonly with inflammatory bowel…