Search Results for: ballooning

Histologic Diagnosis of Inflammatory Skin Diseases

Burns

…hereas a blister induced by sunburn usually occurs with less celerity. Even in a burn early in development, some evidence of ballooning of epidermal keratocytes is discernible. If ballooning is extensive, intraepidermal vesiculation results. If the…

Histologic Diagnosis of Inflammatory Skin Diseases

Pellagra

…s cannot be made without equivocation. Lesions developed fully, however, show pathognomonic changes in the form of extensive ballooning in a band across the upper half of the viable epidermis. Such ballooning is followed always by necrosis and, not…

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

…e dermis and the epidermis; a papulovesicle consists of elements of an urticarial papule with the addition of spongiosis and ballooning; a vesicle develops secondary to extensive ballooning, the color of it sometimes being gray because of necrosis…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…selected be that of “interface dermatitis, vacuolar type,” of “spongiotic dermatitis,” or of “ballooning dermatitis”? If inflammatory cells are distributed lightly, but surely, along the dermoepidermal junction…

Differential Diagnosis in Dermatopathology

Discussions

…iculation. That is not the case for Mucha-Habermann disease; almost always the intraepidermal blister comes about because of ballooning. In both diseases, ballooning tends to progress to vesiculation affiliated with reticular alteration which is…

Histologic Diagnosis of Inflammatory Skin Diseases

Irritant contact dermatitis/Phototoxic dermatitis

…ptotic cells.” Neutrophils are attracted chemotactically to necrotic keratocytes. The blister that results from marked ballooning of keratocytes forms first in the epidermis, but, if the reaction is intense sufficiently, it becomes…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pigmentosa Vesicles in prurigo pigmentosa may come into being by virtue of extensive spongiosis, early in the process, or by ballooning later. Neutrophils are the first inflammatory cells to arrive in the epidermis and are joined there a day or so…

Differential Diagnosis in Dermatopathology

Discussions

…is characterized by spongiosis with little, if any, ballooning, in contrast to the situation in phototoxic dermatitis where ballooning of keratocytes is prominent and spongiosis is not. Severe ballooning in phototoxic dermatitis, accompanied as it…

Differential Diagnosis in Dermatopathology

Allergic contact dermatitis vs. Irritant contact dermatitis

Circular orange-red-blue macule(s) or patch(es) that often becomes a papule(s) or plaque(s) and vesiculates, healing with hyperpigmentation, and that occurs repeatedly at the very same cutaneous and/or mucous membrane site(s), especially the…

Histologic Diagnosis of Inflammatory Skin Diseases

Measles

…s Slight spongiosis Slight ballooning Few individual necrotic keratocytes in the spinous zone, especially in the vicinity of ballooning Few multinucleate epithelial giant cells in foci of spongiosis and ballooning Slight focal parakeratosis…