Search Results for: biopsy

Therapeutic Strategies in Dermatology

Necrobiosis Lipoidica Diabeticorum: Key Points

…ormed but not required. One of the main challenges in managing these patients is that once they have developed ulceration, a biopsy may fail to heal and leads to a chronic wound. On biopsy of NL lesions, the pathology is often squared-off, due to…

Therapeutic Strategies in Dermatology

Balanitis: Overview

…xed drug eruption. Consider the possibility of an allergic contact dermatitis (e.g., from condoms or vaginal hygiene spray). Biopsy patients not responding to these measures. Circumcision will usually result in resolution in refractory cases….

Therapeutic Strategies in Dermatology

Alopecia: Treatment

…nship between doctor and patient. Pitfalls If the diagnosis is not clear or if not responding to treatment, consider a scalp biopsy. Androgenetic alopecia Topical minoxidil (2% solution or 5% solution or foam, such as generic minoxidil or Rogaine)….

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…imicked by factitial ulcers. At the institution of therapy, strong consideration should be given to performing an incisional biopsy for routine histology and cultures, and performing appropriate laboratory tests to exclude the above conditions….

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Clinical Cases

…red nodules, cysts, and sinus tracts with moderate erythema in bilateral axillae Diagnosis: hidradenitis suppurativa No skin biopsy is required Treatment options discussed; patient opts for systemic antibiotics. Rifampin 300 mg bid and clindamycin…

Therapeutic Strategies in Dermatology

Chondrodermatitis Nodularis Helicis: Key Points

…s a crusted ulceration mimicking a cutaneous malignancy. Diagnosis may be made by clinical exam and the symptom of pain, but biopsy of commonly performed to exclude cutaneous malignancies Treatment is aimed at protecting the area with local…

Therapeutic Strategies in Dermatology

Granuloma Annulare: Clinical Case

…Diagnosis: Granuloma annulare Attempt a KOH scraping to evaluate for presence of dermatophyte infestation (ruling out tinea) Biopsy a representative skin lesion for confirmation Perform routine blood work, including complete blood count and…

Therapeutic Strategies in Dermatology

Linear IgA Bullous Dermatosis: Initial Evaluation

Initial Evaluation As with many blistering dermatoses, initial evaluation for LABD includes a punch biopsy at the edge of a fresh blister for hematoxylin and eosin (H&E). Histology demonstrates a subepidermal bulla with a mixture of neutrophils…

Therapeutic Strategies in Dermatology

Pruritic Urticarial Papules and Plaques of Pregnancy: Initial Evaluation

…aring lesions and diffuse erythema may also be seen often later in the disease course. The lesions are highly pruritic. Skin biopsy is rarely necessary as the diagnosis can often be made clinically. Histopathological findings for PUPPP are largely…