Therapeutic Strategies in Dermatology

Chondrodermatitis Nodularis Helicis: Key Points

…sis may be made by clinical exam and the symptom of pain, but biopsy of commonly performed to exclude cutaneous malignancies Treatment is aimed at protecting the area with local measures, with a number of topical, intralesional, and ultimately surgic…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Clinical Cases

…bilateral axillae Diagnosis: hidradenitis suppurativa No skin biopsy is required Treatment options discussed; patient opts for systemic antibiotics. Rifampin 300 mg bid and clindamycin 300 mg b.i.d. is prescribed Intralesional triamcinolone 5 mg/cc i…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

…y comprised of endothelial cells (staining GLUT-1 positive on biopsy) and blood, without organized blood flow. In most cases, HOI represent asymptomatic benign lesions that do not require immediate intervention; options for later treatment may involv…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

…h local radiation. Any suspicious non-healing lesion requires biopsy. Inflammatory bowel disease may cause perirectal and/or genital sinus tracts and abscesses. These may be misdiagnosed as hidradenitis. When to refer to a dermatologist When the di…

Therapeutic Strategies in Dermatology

Erythema Multiforme: Treatment

…. Diagnostic management should entail consideration of a skin biopsy and a reasonable search for potential triggers that can be eliminated or treated. Diagnostic considerations include: viral direct fluorescence antibody (DFA) testing, viral culture,…

Therapeutic Strategies in Dermatology

Aphthous Ulcers (Recurrent Aphthous Stomatitis, Canker Sore): Treatment

…al after three or four weeks warrants evaluation and possible biopsy to rule out malignancy. Aphthae are diagnosed by history and physical exam alone; there is a broad differential for diseases which can manifest with oral ulcerations, and extended w…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Treatment

…phoresis or immunofixation electrophoresis, or by bone marrow biopsy if there is high clinical suspicion. Sweet’s syndrome may be triggered by medications; a review of the patient’s medication list and empiric discontinuation of classic drug triggers…

Therapeutic Strategies in Dermatology

Melanoma: References

…Dermatology, 28:311-315. Morton DL et al (2006) Sentinel-node biopsy or nodal observation in melanoma, NEJM, 355:1307-1317. National Cancer Institute. Melanoma Treatment (PDQ). 7 Nov 2014. Web. http: www.cancer.gov/cancertopics/pdq/treatment/melanoma…

Therapeutic Strategies in Dermatology

Leukocytoclastic Vasculitis: Treatment

…When the diagnosis of palpable purpura is not clear. For skin biopsy of lesions to confirm the diagnosis. A biopsy for direct immunofluorescence (which reveals deposition at cutaneous superficial dermal vessels), in addition to biopsies for hematoxyl…