Therapeutic Strategies in Dermatology

Chondrodermatitis Nodularis Helicis: Key Points

Key Points Chondrodermatitis nodularis helicis (CNH) is an uncommon, strikingly painful lesion on the helix or antihelix of the ear, which often appears as a crusted ulceration mimicking a cutaneous malignancy. Diagnosis may be made by clinical exa…

Therapeutic Strategies in Dermatology

Melanoma: References

References Balch CM et al (2009) Final version of the 2009 AJCC Melanoma staging and classification, JCO, 27: 6199-6206. Chapman PB, Hauschild A, Robert C, et al (2011) Improved survival with vemurafenib in melanoma with BRAF V600E mutation, N Engl…

Therapeutic Strategies in Dermatology

Erythema Multiforme: Treatment

Treatment Initial therapy First-line treatment is supportive care. Diagnostic management should entail consideration of a skin biopsy and a reasonable search for potential triggers that can be eliminated or treated. Diagnostic considerations inclu…

Therapeutic Strategies in Dermatology

Aphthous Ulcers (Recurrent Aphthous Stomatitis, Canker Sore): Treatment

Treatment First-line therapy: Patients with active ulcers should avoid trauma to the oral mucosa (including hard toothbrushes or sharp foods) and limit intake of acidic products which can worsen pain. Topical analgesics and local protective topical…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

Treatment First-line therapy: The first-line therapy for mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-lin…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Treatment

Treatment First-line therapy: The first-line therapy for Sweet’s syndrome is systemic corticosteroids, because it is almost universally effective for treatment of this condition and is rapid in onset. Because a chronic, relapsing/remitting course of…

Therapeutic Strategies in Dermatology

Vascular Birthmarks: Key Points

Key Points Vascular birthmarks are cutaneous vascular lesions present at, or shortly after, birth. They may be categorized as vascular tumors or vascular malformations. The term hemangioma has previously been used to describe many common, typicall…

Therapeutic Strategies in Dermatology

Leukocytoclastic Vasculitis: Treatment

…When the diagnosis of palpable purpura is not clear. For skin biopsy of lesions to confirm the diagnosis. A biopsy for direct immunofluorescence (which reveals deposition at cutaneous superficial dermal vessels), in addition to biopsies for hematoxy…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

Treatment First-line therapy: The first-line therapy should be specified for the affected anatomic site. Skin Initial therapy If the skin is macerated (e.g., moist, weeping), instruct the patient to soak in (or make an applied compress of) dilute…