Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…lly, clinically and molecularly, that the so-called dysplastic nevus is a type of melanocytic nevus and should be managed like other types of melanocytic nevi [1,2]. This reinforces the notion set forth by the late Bernie Ackerman, who asserted more…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…ne hopes by a trained dermatopathologist), usually small nests of relatively round fairly clear cells are seen in a large, relatively symmetrical group that is fairly closely bound. Most of the cells are exactly alike and very few, if any, nevus cell…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Junctional Activity and Active Junctional Nevus?

…ed by him throughout the 1950s and, with less vigor to the end of his life in the 1990s. Remarkably, however, every photomicrograph chosen by Allen to depict active junctional nevus showed indubitable signs of melanoma in situ. That Allen knew the &#…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Clinical Case Studies

Nevus of Ota

…ake any medications. Skin examination revealed a 3 x 7 cm area of gray coalescing macules in the left infraorbital region. There was no associated change in skin texture. No scleral pigment was noted. Figure 1. Nevus of Ota at patient’s init…

Differential Diagnosis in Dermatopathology

Spitz’s nevus, compound type vs. Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…