Histologic Diagnosis of Inflammatory Skin Diseases

Apocrine Units

…is “modified,” as so often is asserted. Nor is the breast a “modified apocrine gland” or a “modified sweat gland.” The breast simply is a distinctive region of the skin and subcutaneous tissue, the latter housing a…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

All constituents of human skin are derived from either ectoderm or mesoderm. The epithelial structures, i.e., epidermis (surface and infundibular), apocrine units, sebaceous units, hair follicles, eccrine units, and nail units, come from ectoderm. M…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

Radiation dermatitis and panniculitis Synonyms Radiodermatitis Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions At a site of previous radiation Individual lesions Poikilodermatous patches and ulcers Course Protract…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Borderline, Minimal Deviation, and Nevoid Melanomas?

“Borderline lesions are encountered in other organ systems. In the category of epithelial neoplasms of the ovary, borderline lesions are common. They are also commonly manifested as papillary lesions of the breast.” Reed RJ. Minimal de…

Histologic Diagnosis of Inflammatory Skin Diseases

Macular and papular (lichenoid) amyloidosis-Cutaneous solely

Macular and papular (lichenoid) amyloidosis—Cutaneous solely Presentation stereotypical Age and sex Women of Asian, Latin, or Middle Eastern ancestry usually Distribution of lesions Macular form most common in the interscapular region, but also seen…

Histologic Diagnosis of Inflammatory Skin Diseases

Muscles

In the skin, smooth muscle occurs in two different unrelated settings. One is in fascicles that form muscles of hair erection and the other is in the wall of arterioles and venules. The fascicles that make up the arrector pili muscle originate from…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphadenosis benigna cutis

Lymphadenosis benigna cutis Synonyms Borrelial pseudolymphoma Presentation stereotypical Age and sex Any age and either sex Distribution of lesions Localized usually to an ear lobe, the nose, a nipple or areola, or the scrotum; lesions on the ear ar…