Search Results for: crohn\'s disease

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ase, which is protean in its presentations but most commonly presents as papules, plaques, lupus pernio, or scar- or tattoo-associated lesions. Introduction Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The therapy of each form is

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…h also frequently affects the muscles. Dermatomyositis can be a sign of internal malignancy, with 20% of patients having an associated cancer (ovarian cancer risk, in particular, is elevated). Patients require thorough evaluation for extracutaneous

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

…mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-line. First steps Medical Culture draining sinus tracts or…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Key Points

Key Points Hidradenitis suppurativa (HS) is a chronic inflammatory process affecting skin bearing apocrine glands; the groin, axillae, and inframammary areas are typically involved. The classic lesions of HS include cysts, nodules, sinus tracts,…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…two key elements: controlling inflammation and optimizing wound care. Inflammatory control may require systemic immunosuppression and/or the use of multiple therapeutic agents in combination. First steps Systemic corticosteroids are the initial…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Initial Evaluation

…nce (DIF); this may be performed by a dermatologist, otolaryngologist, or oral medicine specialist. Patients with skin lesions suspicious for PV should be referred to a dermatologist for a skin biopsy. The diagnosis of PV is made via biopsy of…

Differential Diagnosis in Dermatopathology

Pagetoid Bowen’s disease vs. Extramammary Paget’s disease

An inflammatory process expressed clinically by markedly edematous acuminate papules and edematous plaques situated mostly on the face, upper part of the trunk, and arms, especially the hands, and often accompanied by fever and leukocytosis. It may…