Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

…rapy: The first-line therapy for mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-line. First steps Medical C…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Key Points

…enosum can occur concurrently within areas of HS or at distant sites. Hidradenitis suppurativa is more prevalent in women. Risk factors for disease include obesity, smoking, and Crohns disease. Additional cutaneous associations include acne, pilonid…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…changed frequently to avoid maceration; alternatively, ulcers should be covered by a non-adherent dressing with absorptive features (such as foam or alginate). Removal must be very gentle to avoid pathergy (appearance of disease in sites of trauma)….

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

…mg/day (0.5-1.0 mg/kg/day) for 2-3 weeks, then taper the dose. Subsequent Steps Search for underlying dental or sinus inflammation. The treatment of these hidden foci of infection may lead to improvement of the cheilitis. Crohns disease may p…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

Crohns disease Synonyms Inflammatory bowel disease Regional ileitis Regional enteritis Chronic cicatrizing enteritis Presentation stereotypical Age and sex Young adults; slight predominance of women Distribution of lesions The poles of the ga…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…”s disease” may not have, but rather “herpes simplex recidivans in loco” (which may be joined by a variety of alterations in the skin, including erythema multiforme and erythema nodosum) or of Crohns disease (which is a…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…erficial basal-cell carcinoma vs. Granuloma annulare (Quiz #1) Suppurative dermatitis and spiradenitis following on suppurative infundibulitis (the latter not captured in this section of tissue) secondary to Crohns disease (Quiz #555) Suppurat…