Search Results for: crohn\'s disease

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…he starting dose is 0.2-0.3 mg/kg/day, with gradual escalation of the dose to the therapeutic range of 0.5-1 mg/kg/day. Successful use of alitretinoin in Darier’s disease has recently been reported. Topical tretinoin 0.025% gel or 0.1% cream before…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Treatment

…mild to moderate hidradenitis suppurativa is topical or systemic antibiotics. For very severe disease, systemic immunosuppression, specifically with anti-TNF-alpha inhibitors, may be first-line. First steps Medical Culture draining sinus tracts or…

Therapeutic Strategies in Dermatology

Hidradenitis Suppurativa: Key Points

Key Points Hidradenitis suppurativa (HS) is a chronic inflammatory process affecting skin bearing apocrine glands; the groin, axillae, and inframammary areas are typically involved. The classic lesions of HS include cysts, nodules, sinus tracts,…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

…two key elements: controlling inflammation and optimizing wound care. Inflammatory control may require systemic immunosuppression and/or the use of multiple therapeutic agents in combination. First steps Systemic corticosteroids are the initial…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Initial Evaluation

…nce (DIF); this may be performed by a dermatologist, otolaryngologist, or oral medicine specialist. Patients with skin lesions suspicious for PV should be referred to a dermatologist for a skin biopsy. The diagnosis of PV is made via biopsy of…

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

Melkersson-Rosenthal Syndrome Cheilitis granulomatosa is sudden onset of swelling of the lips which progresses to chronic enlargement. The Melkersson-Rosenthal syndrome diagnosis is made when lip enlargement is accompanied by facial paralysis or…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…oncurrent with the inflammatory disease of the bowel. Involvement of the oral cavity occurs in 10% to 20% of patients. Melkersson-Rosenthal syndrome, in some instances, is a manifestation of Crohns disease. Differential diagnosis clinical…

Differential Diagnosis in Dermatopathology

Pagetoid Bowen’s disease vs. Extramammary Paget’s disease

…e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lymphadenosis benigna cutis), and acral patches and plaques that in time become atrophic (acrodermatitis chronica atrophicans). It may express itself in…