Search Results for: darier\'s sign

Therapeutic Strategies in Dermatology

Keratosis Pilaris: Treatment

…kin lesions and interventions to reduce inflammation are outlined below. Initial therapy A mild soap (e.g., Dove) or a soapless cleanser (e.g., Cetaphil, Cerave) should be used with a mild exfoliating scrub pad or washcloth. This treatment will…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ase, which is protean in its presentations but most commonly presents as papules, plaques, lupus pernio, or scar- or tattoo-associated lesions. Introduction Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating…

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

Therapy First-line therapy: Prompt identification and discontinuation of the offending agent is an essential first step. In most cases, the cutaneous reaction will resolve in 2-5 days without therapy; patients may continue to get new lesions during…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Key Points

Key Points Pyoderma gangrenosum is a type of ulcerating neutrophilic dermatosis. The classic morphology of pyoderma gangrenosum is an ulcer with a violaceous rim and undermined border. PG lesions may develop very rapidly (in days) and may be…

Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis: Treatment

Treatment First-line therapy: The first-line therapy for Grover’s is to suppress pruritus and when possible, reduce inflammation and clear lesions. First steps If TAD is not pruritic, treatment may not be required. A high-potency or superpotent…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Key Points

…tly inherited genodermatosis caused by dysregulation of calcium hemostasis in the keratinocyte that leads to acantholysis (loss of cell-cell adhesion) in the epidermis. Clinically, it manifests with macerated, eroded plaques primarily in the…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Initial Evaluation

…nd nails. Any lesions with significant crusting (or other signs of infection such as surrounding/spreading erythema, tenderness, or purulent exudates) are swabbed for bacterial culture. A skin biopsy from lesional skin is performed and submitted for…

Therapeutic Strategies in Dermatology

Syphilis (Lues): Key Points

…n and the organ systems involved. Five subtypes of syphilis can be distinguished: primary, secondary, or early syphilis of less than 1 year’s duration; infection of indeterminate length, or more than 1 year’s duration; neurosyphilis;…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Initial Evaluation

…g of the nasal tip. Face and neck involvement is common. Other body areas can be affected with more erythema or more dull, less erythematous eczematous plaques. Excoriated, fissured, lichenified erythematous plaques of atopic dermatitis in a…