Dermatology Practical & Conceptual

Dermoscopic findings in a patient with multiple piloleiomyomas

…opic evaluation, piloleiomyoma has characteristics similar to dermatofibroma with a thin peripheral pigmented network and central scar-like area. Some of the piloleiomyomas analyzed in this patient also presented with hyperpigmented circular and/or e…

Differential Diagnosis in Dermatopathology

Discussions

…tudied as they should be. A case in point is the surface of a dermatofibroma where a shave biopsy may result in overdiagnosis of the lesion as a superficial type of basal-cell carcinoma, rather than as a hyperplastic response to the inflammatory proc…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…ribed it, may be encountered in such dissimilar conditions as dermatofibroma and malignant fibrous histiocytoma, not only in “juvenile xanthogranuloma.” Figure 5.187 Sarcoidal granuloma. A collection such as this one of epithelioid his…

Differential Diagnosis in Dermatopathology

Discussions

Despite the differences biologic between dermatofibroma (an inflammatory process) and desmoplastic (fibrosing, largely intradermal) Spitz’s nevus (a benign neoplastic process), the two conditions have many attributes morphologic in common. Bot…

Differential Diagnosis in Dermatopathology

Discussions

Dermatofibroma and dermatofibrosarcoma protuberans are lesions made up of dense diffuse infiltrates of mesenchymal cells in company with bundles of collagen, the two together occupying at least much of the thickness of the dermis and sometimes part…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…e modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lymphoma” is nothing other tha…

Differential Diagnosis in Dermatopathology

Discussions

Early changes in papulonodular lesions of dermatofibromas are similar, in many respects, to those in Kaposi’s sarcoma. Both are dome-shaped and consist of proliferations that are highly cellular. Most of the cells are oval and they are joined…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…garis, and vaccination scars Differential diagnosis clinical Dermatofibroma is a distinctive type of scarring process that tends to be oval or round, hyperpigmented, and dimpled when it is squeezed between fingers. Findings histopathologic Early Gr…