Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…spirochetes in rupial syphilis, of fungi in an expression of dermatophytosis (Fig. 5.322 A-D), and in diseases for which no cause is known, such as psoriasis. In short, the appearance of a pustule, as it is assessed by conventional microscopy, commu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Id Reactions?

…nd vesicular responses at a site distant to florid lesions of dermatophytosis on the feet or of allergic contact dermatitis consequent to dyes or other sensitizing components in shoes. Those spongiotic and spongiotic vesicular dermatitides are indist…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…es in the dermis tends to be linear in adnexocentric fashion. Dermatophytosis may be accompanied episodically by numerous lymphocytes in an epidermis that houses little spongiosis, but hyphae are detectable in the cornified layer. Clues to specific…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…n is basket-weave = Tinea versicolor ¬†Unlike the situation in dermatophytosis, in which the cornified layer usually is altered by compact orthokeratosis (a consequence of persistent rubbing) or parakeratosis that sometimes houses neutrophils, the cor…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…ted by tiny vesicles on the hands of patients who have florid dermatophytosis at another site, usually the feet, or for an analogue of that phenomenon such as widespread vesicles that appear subsequent to injudicious treatment, e.g., with Gentian vio…

Histologic Diagnosis of Inflammatory Skin Diseases

Tinea versicolor

…ypified by longer and thinner pseudohyphae and larger spores. Dermatophytosis is characterized by longer, thinner hyphae. Laboratory confirmation Potassium hydroxide preparation reveals short, stubby, blunt-ended hyphae accompanied by round spores….

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…#8220;bite,” as well as to polymorphous light eruption, dermatophytosis, Sweet’s syndrome, erysipelas, and several other “acute” inflammatory conditions that are either devoid of eosinophils or sport relatively few of them. An…