Search Results for: diffuse neuroendocrine system (anachronistic)

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ficial morphea)     Interstitial Granulomatous Infiltrate Histiocytes, sometimes multinucleate, splayed focally or diffusely among bundles of collagen in the reticular dermis (and sometimes in septa of the subcutaneous fat). Click image to…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…dominance of mast cells = Urticaria pigmentosa This particular expression of urticaria pigmentosa is superficial, dense, and diffuse, in contrast to that of telangiectasia macularis eruptiva perstans which is superficial, perivascular, and…

Extensive regression in pigmented skin lesions: a dangerous confounding feature

Extensive regression in pigmented skin lesions: a dangerous confounding feature

…e arm of a 50-year-old man, who was recently diagnosed with metastatic melanoma of the ipsilateral axillary lymph nodes. (B) Diffuse granular pattern in the absence of melanoma-specific criteria in dermoscopy. Scar-like depigmented areas (black…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…soriasiform nodular pattern in which lymphocytes predominate overwhelmingly is a clue to mycosis fungoides A dense patchy or diffuse infiltrate of lymphocytes, together with innumerable multinucleate histiocytic giant cells (that often sport large…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…n bodies that are known to violate it. The foreign body illustrated here is Gelfoam, a styptic employed commonly. 10.38.14A: Diffuse dermatitis, granulomatous + 10.38.14B: Macrophages with abundant finely vacuolated and clear cytoplasm = Silicone…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Telogen Effluvium—An Inflammatory Disease?

…a relatively synchronous fashion. The extent of the process depends upon the number of follicles involved but it is usually diffuse. The patient may complain of increased hair fall that does not result in apparent baldness, or the hair loss may be…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

…he diagnosis of erythema nodosum leprosum requires the presence, clinically, of painful and tender nodules in a patient with diffuse or nodular lepromatous leprosy, whereas a diagnosis of Lucio’s phenomenon is established clinically on the…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…nd plaques. Histoid leprosy occurs as violaceous nodules in persons whose lepromatous leprosy is resistant to treatment; the diffuse infiltrate of foam cells is accompanied by prominent fibroplasia. Reactional states, i.e., erythema nodosum…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…eczema and pemphigoid and we give a brief account of nine cases. The particular histological features are dermal oedema with diffuse infiltration of the dermis with eosinophils and phagocytic histiocytes together with scattered “flame…

Histologic Diagnosis of Inflammatory Skin Diseases

Urticaria pigmentosa

…istopathologic Macular and papular types Nodular type Bullous type Correlation clinicopathologic Nodules are formed by dense diffuse monomorphous infiltrates of mast cells. Smaller versions of them, i.e., dome-shaped papules, are made up of fewer…