Therapeutic Strategies in Dermatology

Epidermolysis Bullosa: Overview

…All forms are inherited in autosomal dominant fashion. . This disease may be generalized and severe (EB herpetiformis of Dowling-Meara), generalized and mild to moderate (Koebner type), or localized to the acral areas (Weber-Cockayne type). Scarring…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

Degosdisease (malignant atrophic papulosis) Synonyms Degos’ syndrome Malignant atrophic papulosis Papulosis atrophicans maligna Koehlmeier-Degos syndrome Thromboangiitis cutaneointestinalis disseminata Fatal cutaneointestinal syndrome…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

…broad front, rather than in discrete foci. Galli-Galli’s disease is reputed to show findings of both Dowling-Degosdisease and Darier’s disease, namely, nubbins of hyperpigmented epidermal rete ridges in which are foci of acantholy…

Differential Diagnosis in Dermatopathology

Pagetoid Bowen’s disease vs. Extramammary Paget’s disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…osum, there is no granulomatous panniculitis in Behçet”s disease. In some lesions of Behçet”s disease, fibrin is present in the wall of venules and thrombi are found in the lumen of them. Those changes in the deep reticular dermis and sub…