Differential Diagnosis in Dermatopathology


…changes that are more focal, parakeratosis more prominent, and dyskeratosis more extensive in the granular zone and cornified layer. Hailey-Hailey like Darier’s disease and unlike pemphigus vulgaris, is marked by both acantholysis and dyskerato…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases


Images 10.86.1A: Perivascular dermatitis, lymphocytic + 10.86.1B: Thin cornoid lamella = Porokeratosis, disseminated superficial actinic ┬áThe cornoid lamella on the left springs from an infundibulum. Cornoid lamellae also may emanate from…

Differential Diagnosis in Dermatopathology

Epidermolytic hyperkeratosis vs. Plane wart

A keratotic condition of the palms and soles, inherited usually, but sometimes acquired, in which involvement may be diffuse, circumscribed (including striate), or punctate….

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

Error: Abortive is an accurate modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lympho…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Darier’s disease (keratosis follicularis) Grover’s disease (transient acantholytic dermatosis) 1. No evidence of excoriation usually 1. Erosions, ulcerations, and scale-crusts, i.e., evidences of excoriation, present often 2. Focal…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology


“… this distinctive type of necrosis (apoptosis)…has previously been called shrinkage necrosis on morphological grounds.” Kerr JFR. Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implicatio…