Dermatology Practical & Conceptual

Dermoscopic findings in bowenoid papulosis: report of two cases

…t al.) Figure 4. Mild hyperkeratosis, irregular acanthosis, dyskeratosis and mitosis (H&E X10). (Copyright: ©2014 Marcucci et al.) Figure 5. Cytological atypia, dyskeratosis and mitosis (H&E X40). (Copyright: ©2014 Marcucci et al.) Case…

Differential Diagnosis in Dermatopathology

Discussions

…changes that are more focal, parakeratosis more prominent, and dyskeratosis more extensive in the granular zone and cornified layer. Hailey-Hailey like Darier’s disease and unlike pemphigus vulgaris, is marked by both acantholysis and dyskerato…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

Abstract Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections. Purpose: To review the histologic differential di…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.86.1A: Perivascular dermatitis, lymphocytic + 10.86.1B: Thin cornoid lamella = Porokeratosis, disseminated superficial actinic  The cornoid lamella on the left springs from an infundibulum. Cornoid lamellae also may emanate from…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Darier’s disease (keratosis follicularis) Grover’s disease (transient acantholytic dermatosis) 1. No evidence of excoriation usually 1. Erosions, ulcerations, and scale-crusts, i.e., evidences of excoriation, present often 2. Focal…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

“… this distinctive type of necrosis (apoptosis)…has previously been called shrinkage necrosis on morphological grounds.” Kerr JFR. Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implicatio…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

Error: Abortive is an accurate modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lympho…