Search Results for: epidermis

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…is. They may be found in evolving, smooth, and scaly papules, as well as in crusted ones. The presence of neutrophils in the epidermis of secondary syphilis is a sure sign that the epidermis swarms with spirochetes that can be demonstrated easily in…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…of spongiotic vesiculation = Bullous pemphigoid, vesicular A blister in bullous pemphigoid usually is positioned beneath the epidermis, but sometimes is situated in the epidermis, it being an exaggeration of spongiosis induced by eosinophils. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…osinophils and lymphocytes in perivascular and interstitial array in the dermis, in spongiotic foci in the lower part of the epidermis, and, in company with neutrophils in the ballooned, necrotic surface epidermis + 10.5.23C + 10.5.23D = Response to…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…atitides are devoid of any sign of vasculitis, being dermatitides, not vasculitides. Error: Caterpillar bodies in the viable epidermis above a blister situated beneath the epidermis are specific for porphyria cutanea tarda. Reason: The distinctive…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…us, but also to dermatomyositis. Scattered neutrophils and nuclear “dust” of neutrophils immediately beneath the epidermis and in the epidermis is a clue to a very early stage of discoid lupus erythematosus (“butterfly blush”…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…e, the outer sheath extends all the way from the bottom of the bulb to the base of the infundibulum. The infundibulum, being epidermis, is continuous with surface epidermis. Soon after a follicle enters the involutional stage of a cycle, i.e.,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ion of epidermis beneath the necrotic epidermis = Irritant contact dermatitis As a consequence of the effect of the irritant, keratocytes in surface epidermis became ballooned severely and then necrotic. Beneath the necrotic epidermis a new…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ing dermatofibroma. 10.20.19A: Fibrosing dermatitis + 10.20.19B: Follicular germs and a sebaceous lobule continuous with the epidermis = Dermatofibroma Induction of folliculosebaceous structures from epidermis by fibrocytes of dermatofibroma, those…