Differential Diagnosis in Dermatopathology

Differential Diagnosis

…s and pustules, and necrosis) uncommon 9. Evidence of injury to the epidermis (spongiosis and ballooning, intraepidermal vesicles and pustules, and necrosis) nearly invariable 10. Erosion and ulceration uncommon 10. Erosion and ulceration common…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Primary and Secondary Lesions?

…econdary lesions, by contrast, are said to be scales, crusts, erosions, ulcers, excoriations, lichenification, and fissures. Regrettably, the concept of primary and secondary lesions is flawed beyond redemption. All so-called primary lesions of the s…

Clinical Case Studies

Graft-Versus-Host Disease

…nine months remained asymptomatic. Figure 6. Only a small erosion is left after intraoral PUVA treatment. CONTRIBUTORS Nathan S. Uebelhoer, DO, SkinCare Physicians, Chestnut Hill, Massachusetts Andrew Bookwater, DDS, Department of Dentistry, U.S….

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…r both together in the same lesion) (Fig. 5.231 A&B), and erosion and/or ulceration (Fig. 5.232 A&B). In all three major types of small-vessel vasculitis, in addition to venules in the dermis being affected, small veins in the subcutaneous fa…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…r dermis Edema of the papillary dermis Epidermal necrosis and erosion or ulceration Fully developed Perivascular lymphoplasmacytic infiltrates around venules in at least the upper part of the dermis Fibrin thrombi in venules in the dermis and, some…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Chondrodermatitis Nodularis Helicis?

…. When animated scratching or analogous trauma supervenes, an erosion or ulceration develops, which is covered by crust. Seated beneath an ulcer or at the base of affected infundibula that may house a plug of cornified cells is a bolus of fibrin. Rub…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…is fungoides, plaque 1. Papules and nodules 1. Plaques 2. Erosion and/or ulceration common 2. No erosion or ulceration usually 3. Parakeratosis often contains neutrophils 3. Ortho- and parakeratosis; no neutrophils 4. Wedge-shaped necrosis an…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Diabetic Dermopathy?

…nd the upper dermis. Erythrocytes were found outside vessels. Erosion of the epidermis was found in some sections. In early dermopathy, the vessels in the papillary layer of skin and adipose tissue were numerous. Both melanin and hemosiderin were fou…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…epidermis = Hailey-Hailey disease Despite the presence of an erosion that obscures many changes essential for diagnosis, that still can be accomplished in Hailey-Hailey disease on the basis of findings in this section; this is Hailey-Hailey disease,…

Dermatology Practical & Conceptual

From the Dermatologikum Hamburg: Quiz

…all elderly women, who presented themselves with pustules and erosions on the scalp [1]. Lesions were not responsive to antibiotics but resolved on topical treatment with potent corticosteroids. Since 1979, a number of case reports and a few studies…