Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…nd individual lesions of it are papules that ulcerate rarely. Erysipelas develops rapidly, has a border marked by pseudopods and is associated with fever. Angioedema develops quickly and responds within hours to administration systemic of corticoster…

Histologic Diagnosis of Inflammatory Skin Diseases

Borreliosis (erythema migrans)

…laques that do not tend to “clear” in the center. Erysipelas does not show “clearing” in the center of the lesion and, moreover, it is warm, vis-à-vis the surrounding normal skin, and painful. Miscues clinical as clues to dia…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

An inflammatory process caused by one of several bacteria, especially Streptococcus pyogenes, and manifested clinically as erythematous patches and erythematous edematous plaques with scalloped outlines upon which vesicles and bullae, some of them h…

Histologic Diagnosis of Inflammatory Skin Diseases

Hypodermitis sclerodermiformis

…lly and may be misinterpreted clinically as thrombophlebitis, erysipelas, or panniculitis, such as that of erythema nodosum or erythema induratum. As the disease progresses, fibrosis develops, resulting in a depressed “plaque” with change…

Histologic Diagnosis of Inflammatory Skin Diseases

"Folliculitis" (Infundibulitis)

…cutaneous/mucous infections. Impetigo, folliculitis/furuncle, erysipelas] Ann Dermatol Venereol 2002;129(10 Suppl):S47-52. Tardio ML, Fasano D, Marucci G, Collina G. [Hyperkeratosis follicularis et parafollicularis in cutem penetrans (Kyrle’s d…

Differential Diagnosis in Dermatopathology

Discussions

…flammatory: red, edematous, and indurated (similar to that in erysipelas) because of obstruction of lymphatics by the neoplastic cells Telangiectatic: purple papules, nodules, and hemorrhagic patches and plaques that resemble vascular neoplasms N…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…onses to assaults by arthropods, Mucha-Habermann disease, and erysipelas, may be either intraepidermal, subepidermal, or both together in the same section of tissue. Subepidermal vesicles alone occur almost always as a consequence of extensive edema…