Search Results for: extramammary paget\'s disease

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…h also frequently affects the muscles. Dermatomyositis can be a sign of internal malignancy, with 20% of patients having an associated cancer (ovarian cancer risk, in particular, is elevated). Patients require thorough evaluation for extracutaneous

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…he starting dose is 0.2-0.3 mg/kg/day, with gradual escalation of the dose to the therapeutic range of 0.5-1 mg/kg/day. Successful use of alitretinoin in Darier’s disease has recently been reported. Topical tretinoin 0.025% gel or 0.1% cream before…

Therapeutic Strategies in Dermatology

Pruritus Ani: Overview

…worn; men should wear loose trousers and cotton boxer undershorts. If there is a history of lumbosacral disc disease, the possibility of a neuropathic cause should be considered. Subsequent Steps The patient should expect symptomatic relief within…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

…n Initial therapy If the skin is macerated (e.g., moist, weeping), instruct the patient to soak in (or make an applied compress of) dilute Burow’s solution 1: 40 b.i.d. for 15 minutes daily throughout the treatment course. Prescribe nystatin…

Therapeutic Strategies in Dermatology

Candidiasis: Key Points

…ogenital mucosal sites. Predisposing factors include obesity, diabetes, antibiotic or corticosteroid treatments, immunosuppression, removable prostheses, and chronic or frequent exposure to moisture including saliva, fecal and urinary incontinence….

Therapeutic Strategies in Dermatology

Candidiasis: Initial Evaluation

Initial Evaluation Candidiasis Intertriginous Oral Paronychia Differential diagnosis Inverse pityriasis rosea Deficiency dermatitis (such as zinc deficiency, aka acrodermatitis enteropathica) Allergic or irritant contact dermatitis Inverse…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease: Initial Evaluation

…nd nails. Any lesions with significant crusting (or other signs of infection such as surrounding/spreading erythema, tenderness, or purulent exudates) are swabbed for bacterial culture. A skin biopsy from lesional skin is performed and submitted for…

Differential Diagnosis in Dermatopathology

Pagetoid Bowen’s disease vs. Extramammary Paget’s disease

…e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lymphadenosis benigna cutis), and acral patches and plaques that in time become atrophic (acrodermatitis chronica atrophicans). It may express itself in…