Search Results for: fibrin

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…ingstone, 2002:396. “Features that favor the diagnosis of PLEVA are the dense perivascular lymphocytic infiltrate with fibrinoid necrosis, which has been referred to as ‘lymphocytic vasculitis’, and the presence of basilar…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…ules, and vesicles, some with a gray roof, as a consequence of infarction secondary to occlusion by thrombi in the lumen and fibrin in the wall of venules. Urtica never is associated with leukocytoclasis of neutrophils. Clue to specific diagnosis…

Differential Diagnosis in Dermatopathology

Subcutaneous granuloma annulare vs. Rheumatoid nodule

A type of small-vessel vasculitis (venulitis) of the skin, occurring especially in the vicinity of the ankle, characterized at first by purpuric macules and patches that, in time, may become hemorrhagic blisters that ulcerate and heal with white,…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…specificity, and, for that reason, it should be avoided in favor of appellations for specific, definable substances, such as fibrin, erythrocytes, keratocytes, amyloid, and colloid. “ID” [Gk. –ides (son or daughter, descendent)]: A…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…ogically, the small vessels of the mid and lower levels of the dermis show endothelial proliferations, hyaline degeneration, fibrin plugs, and thrombosis. A perivascular hemorrhage may be present. Because of the absence of polymorphonuclear…

Histologic Diagnosis of Inflammatory Skin Diseases

Septic vasculitis

…y nuclear “dust” of neutrophils, whereas septic vasculitis is devoid of it; leukocytoclastic vasculitis exhibits fibrin within the wall of venules and no thrombi in the lumen of them, whereas in septic vasculitis, fibrin is not found in…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pus erythematosus, those diseases being of very different character, despite their being alike histopathologically. Note the fibrin in association with neutrophils in the incipient subepidermal vesicle. 10.19.15A: Vesicular dermatitis, subepidermal…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…erforating” granuloma annulare results from extrusion of material in the center of a palisaded granuloma, i.e., mucin, fibrin, degenerated collagen, and nuclear “dust,” situated in the upper part of the dermis through the epidermis…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…bnormal nuclei and stellate cytoplasm in zones of sclerosis Decreased number of epithelial structures of adnexa Subepidermal fibrin often Vacuolar alteration along the dermoepidermal junction in conjunction with a few scattered lymphocytes…