Search Results for: fibrin

Histologic Diagnosis of Inflammatory Skin Diseases

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…arthritis to acute myelogenous leukemia. These are not the changes of leukocytoclastic vasculitis because of the absence of fibrin from the wall of venules. 10.102.5A: Nodular and diffuse dermatitis, superficial, neutrophils mostly + 10.102.5B:…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…; some are those of severe stasis. 10.62.4A: Vasculitis, small-vessel type, mixed-cell and panniculitis, lobular + 10.62.4B: Fibrin in the wall and thrombi in the lumen of venules in company with neutrophils mostly, but also lymphocytes = Livedo…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…ules, and vesicles, some with a gray roof, as a consequence of infarction secondary to occlusion by thrombi in the lumen and fibrin in the wall of venules. Urtica never is associated with leukocytoclasis of neutrophils. Clue to specific diagnosis…

Differential Diagnosis in Dermatopathology

Subcutaneous granuloma annulare vs. Rheumatoid nodule

A type of small-vessel vasculitis (venulitis) of the skin, occurring especially in the vicinity of the ankle, characterized at first by purpuric macules and patches that, in time, may become hemorrhagic blisters that ulcerate and heal with white,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…pus erythematosus, those diseases being of very different character, despite their being alike histopathologically. Note the fibrin in association with neutrophils in the incipient subepidermal vesicle. 10.19.15A: Vesicular dermatitis, subepidermal…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…specificity, and, for that reason, it should be avoided in favor of appellations for specific, definable substances, such as fibrin, erythrocytes, keratocytes, amyloid, and colloid. “ID” [Gk. –ides (son or daughter, descendent)]: A…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…ogically, the small vessels of the mid and lower levels of the dermis show endothelial proliferations, hyaline degeneration, fibrin plugs, and thrombosis. A perivascular hemorrhage may be present. Because of the absence of polymorphonuclear…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…erforating” granuloma annulare results from extrusion of material in the center of a palisaded granuloma, i.e., mucin, fibrin, degenerated collagen, and nuclear “dust,” situated in the upper part of the dermis through the epidermis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…thelioid histiocytes. Rheumatoid nodule is a granulomatous panniculitis (and sometimes dermatitis) in which huge deposits of fibrin are surrounded by thin epithelioid histiocytes arrayed in a palisade. From the preceding brief descriptions, it is…