A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eruptive Vellus Hair Cyst?

…e hairs that eventually become lodged within the lipid-filled cystic cavity. Sometimes apocrine glands and ducts, and even eccrine glands and ducts, are affiliated with the cyst. Episodically, a nonepithelial component appears in the hamartoma, namel…

Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…the isthmus of the hair follicle, actually is not part of the folliculosebaceous unit, but is epidermis, that particular epithelium being divisible morphologically in two parts continuous with each other, that is, surface and infundibular. The apocri…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

…development or in postnatal humans. The epithelial adnexa are folliculo-sebaceous-apocrine units on one hand and eccrine units on the other; the nonepithelial adnexa are smooth muscles, nerves, and blood vessels. Each of those normal adnexal structur…

Differential Diagnosis in Dermatopathology

Discussions

Infundibulo-folliculo-sebaceous cystic hamartoma and steatocystoma are both cystic hamartomas. Neither is simply a cyst because the structures that comprise each of them are not mere epithelium-lined sacs that house fluid or solid elements, but are…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

…that condition being, at least in that setting, a distinctive hamartoma, one inherited in autosomal-dominant fashion. They did not consider what they called the sporadic solitary form of the hamartoma to be inherited. In 1991 Metcalf and others exami…