Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

Malignant neoplasms of B-lymphocytes especially that present themselves usually as papules, nodules, and tumors, sometimes solitary but at other times numerous, and often in clusters on any anatomic site. When “primary,” B-cell lymphomas o…

A Clinical Atlas of 101 Common Skin Diseases

Ichthyoses

Noninflammatory scaly disorders in which polygonal gray or brown scales tend to be elevated at their periphery, causing them to appear to be separated from contiguous scales, findings that are seen in three conditions, namely, ichthyosis vulgaris (a…

Dermatology Practical & Conceptual

Balloon cell melanoma in primary care practice: a case report

…thelioid melanocytes, exhibiting a pseudo-xanthomatous balloon cell change in their cytoplasm, and pleomorphic vesicular nuclei with nucleoli. These cells did not mature with descent, exhibited 4 mitoses per mm2 and filled the dermis to a depth of 2…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…HX) but this would imply that intraepidermal Langerhans’ cells [LC] or LC in the dermis represent pathologic, or at least, not “normal” cells, which is difficult to accept. If, on the other hand, the LC is considered a specific hist…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Basal-Cell Carcinoma Common in Nevus Sebaceus?

…ocytes of the inner sheath, and, episodically as pale or clear cells of outer sheath, as well as epidermal epithelium like that of the infundibulum. All of this comes about because trichoblasts are abnormal equivalents of germinative cells in a embry…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

…(CTCL), also known as mycosis fungoides, consists of malignant cells that resemble mature T cells. Vargo N. Cutaneous malignancies: KA, CTCL, and KS. Dermatol Nurs. 2006;18(3):270,277. New designations for diseases do not always represent an advanc…

Dermatology Practical & Conceptual

The dermatoscopic universe of basal cell carcinoma

…5–9. Giacomel J, Zalaudek I. Dermoscopy of superficial basal cell carcinoma. Dermatol Surg. 2005;31:1710–3. Sanchez-Martin J, Vázquez-López F, Perez-Oliva N, et al. Dermoscopy of small basal cell carcinoma: study of 100 lesions 5 mm or less in di…

Histologic Diagnosis of Inflammatory Skin Diseases

Adult T-cell leukemia/Lymphoma

Adult T-cell leukemia/Lymphoma Presentation stereotypical Age and sex No predilection for sex. Middle-aged individuals from southern Japan and Caribbean Islands. Distribution of lesions Widespread Arrangement Scattered discrete lesions Individual le…