Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…onally deficient. This disorder is classified as single-system disease, multisystem disease, or multisystem disease with organ dysfunction. The skin is one of the most frequently affected organs in patients with both localized (skin only) and multisy…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…atment First-line therapy: The first-line therapy for Darier’s disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Darier’s disease is systemic retinoids. Isotretinoin and acitretin are equally e…

A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Therapeutic Strategies in Dermatology

Cicatricial Pemphigoid: Overview

…ess may not always be avoided. Treatment First Steps For oral disease apply superpotent topical steroids in ointment base or Orobase to affected areas. For gingival disease, dental trays filled with corticosteroid ointment worn for 6-8 hours daily m…

Therapeutic Strategies in Dermatology

Atopic Dermatitis: Treatment

…elf (including site of application) or use of a treatment plan handout may be helpful to avoid under- or over-treatment of skin disease. See patient handout  Treatment Plan for Atopic Dermatitis The simplest treatment regimen is highly recommended,…

Therapeutic Strategies in Dermatology

Hand Dermatitis: References

References Coenraads PJ (2012) Hand eczema, NEJM, 367: 1829-1837. Bissonnette R et al (2010) Redefining treatment options for chronic hand eczema, JEADV, 24 (Suppl.3): 1-20. Dirschka T et al (2008) An open-label study assessing the safety and effica…

Therapeutic Strategies in Dermatology

Aphthous Ulcers (Recurrent Aphthous Stomatitis, Canker Sore): Key Points

…l diagnosis can include oral involvement of inflammatory bowel disease, gluten sensitivity, Behçet’s syndrome, herpes simplex virus infection, other infections including syphilis, gonorrhea, coxsackievirus infection (hand-foot-mouth disease), and oth…

Therapeutic Strategies in Dermatology

Hand Dermatitis: Clinical Case

…benefit Initial evaluation Healthy appearing male Bilateral hands with hyperkeratotic erythematous plaques with fissures present at the fingertips Diagnosis: hand dermatitis Recommend patch testing Soaks in tap water for 10 minutes twice daily fol…