Search Results for: hodgkin\'s disease

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ase, which is protean in its presentations but most commonly presents as papules, plaques, lupus pernio, or scar- or tattoo-associated lesions. Introduction Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The therapy of each form is

Therapeutic Strategies in Dermatology

Dermatomyositis: Key Points

…h also frequently affects the muscles. Dermatomyositis can be a sign of internal malignancy, with 20% of patients having an associated cancer (ovarian cancer risk, in particular, is elevated). Patients require thorough evaluation for extracutaneous

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomatoid Papulosis

Macaulay first coined the diagnostic term “lymphomatoid papulosis” (LyP) in 1968, although the disease process was first published more than a decade earlier by Dupont and colleagues under the moniker “histiomonocytic reticulosis.” LyP is a rare…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…de the cutaneous surface (often including the face) and mucosal surfaces of the mouth (palate, gingiva, buccal mucosa) and less commonly the pharynx and vocal folds and anogenital mucosa. The disease often begins in the oral mucosa, with only…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…d by IgA autoantibodies to epidermal transglutaminase. Dapsone is the first-line therapy for DH. Strict gluten avoidance is essential. Though gluten avoidance ultimately may prevent recurrence of DH flares, avoidance of gluten as sole treatment of…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Treatment

…as a marker of disease activity and likelihood of future relapse. Treatment is aimed at achieving a rapid and sustained remission with the eventual goal of maintenance with low-dose therapy, or ideally tapering off all treatment. Initial remission…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Key Points

…imentation rate. Extracutaneous manifestations of Sweet’s syndrome may occur. Sweet’s syndrome may be idiopathic or seen in association with other systemic illnesses, most commonly malignancy (especially hematologic), connective tissue disease,…