Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…se from the simulator of it, e.g., focal parakeratosis, focal hypergranulosis, many individual necrotic keratocytes (some of them in clusters), and the presence at times of eosinophils; each of those signify likelihood, in the setting of a lichenoid…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen sclerosus et atrophicus

…lichen simplex chronicus, namely, compact orthokeratosis and hypergranulosis Late All the findings in fully developed lesions, except the absence of inflammatory cells When rubbed persistently, the addition of prominent compact orthokeratosis and…

Histologic Diagnosis of Inflammatory Skin Diseases

Traction alopecia

…ous tracks are widened markedly by thick bundles of collagen. Hypergranulosis of infundibula and permanent alopecia are denominators in common to both conditions. Clue to specific diagnosis histopathologic On a scalp, thickened bundles of collagen p…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…broplasia in the upper part of the dermis, slight acanthosis, hypergranulosis, and compact orthokeratosis = Allergic contact dermatitis, late  The compact orthokeratosis and hypergranulosis are signs of rubbing forcefully and persistently; the fibros…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…in the interstitium of the reticular dermis, and acanthosis, hypergranulosis, and compact orthokeratosis + 10.5.33C + 10.5.33D = Response to an assault by an arthropod with lichen simplex chronicus imposed on it  The findings in the der…

Differential Diagnosis in Dermatopathology

Alopecia of discoid lupus erythematosus vs. Alopecia of lichen planus

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid discoid lupus erythematosus

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…