Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perforating Diseases?

“Perforating dermatoses: . . . various cutaneous disorders are discussed in which the process of perforation and elimination of various tissue components plays a major role in the basic pathologic mechanism. These include perforating granulom…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

“A relationship most likely exists between the verruciform appearance of the epithelium and the underlying foam cells. . . . One might suspect that epithelial breakdown, from some as yet unknown cause may secondarily elicit a foam-cell respo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Reactive Perforating Collagenosis?

…d bullous congenital ichthyosiform erythroderma (epidermolytic hyperkeratosis) for the ichthyoses. It is likely that what Kyrle described in diabetic patients as hyperkeratosis follicularis et parafollicularis in cutem penetrans was simply “per…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.60.1A: Perivascular dermatitis, interface, focally lichenoid + 10.60.1B: Obscuration of the dermoepidermal junction by lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, and compact orthokeratosis = Lichen planus, ear…

Dermatology Practical & Conceptual

Dermoscopic findings in a patient with multiple piloleiomyomas

Abstract Piloleiomyoma can manifest itself as a pigmented lesion and part of the differential diagnosis with other pigmented skin lesions. However, we are not aware of previous descriptions in the literature of the dermoscopic features of piloleiomy…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.11.1A: Perivascular dermatosis, lichenoid + 11.11.1B: Lymphocytes, many necrotic keratocytes and a subepidermal cleft = Lichen planus-like keratosis, earlyBecause lichen planus-like keratosis often is misinterpreted…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.90.1A: Perivascular dermatitis, psoriasiform + 10.90.1B: Lymphocytes and neutrophils around venules, dilated tortuous capillaries in edematous dermal papillae, spongioform pustules, and tiers of neutrophil-containing mounds of p…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

Error: Abortive is an accurate modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lympho…