Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dysplasia?

…Clark et al. wrote that the “Term atypical melanocytic hyperplasia as used by us is synonymous with melanocytic dysplasia….” (Clark et al. Arch Dermatol 1978). In 1980, they averred that “histologically, the sine qua non of t…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…s, eczematization, eczematid, eczematogenic, and eczematosis. HYPERPLASIA [Gk. hyper (above) + plassein (to form)]: An increase in the absolute number of non-neoplastic cells in a tissue. Inherent in the term is the concept, derived from classic path…

Differential Diagnosis in Dermatopathology

Discussions

Both angiolymphoid hyperplasia with eosinophilia and angiosarcoma are processes pathologic that involve endothelium-lined blood vessels. Whereas angiolymphoid hyperplasia with eosinophilia is a vascular malformation that comes into being by virtue o…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

…o wit, verrucous silhouette, parakeratosis, marked papillated hyperplasia, clear spaces of various sizes around nuclei of keratocytes in the upper half of the surface epithelium, slight arborization (i.e., inward turning of outermost elongated epithe…

Differential Diagnosis in Dermatopathology

Discussions

Both sebaceous hyperplasia and nevus sebaceus of Jadassohn consist of abnormalities of sebaceous glands but the former, as the name denotes, is a hyperplasia, whereas the latter is a hamartoma that involves not only sebaceous units, but other adnexa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

…ial phase may be said to constitute the stage of premalignant hyperplasia (Stage I).” Clark WH Jr. A classification of malignant melanoma in man correlated with histogenesis and biologic behavior. In: Montagna W, Hu F, eds. Advances in biology…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

…40]. Spitz nevi exhibit a prominent epidermal or infundibular hyperplasia possibly associated with syringoadnexotropism, neurotropism or myotropism [21]. In the center, melanocytes disposed as solitary units or in nests may be present above the dermo…