Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dysplasia?

…of dysplastic nevi, namely, persistent lentiginous melanocytic hyperplasia, atypical melanocytic hyperplasia, lamellar fibroplasia, concentric fibroplasias, and lymphocytic infiltrates, are also found in melanomas. In brief, their criteria do not per…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…the term is the concept, derived from classic pathology, that hyperplasia ceases when the stimulus responsible for it is withdrawn. But the concept of hyperplasia is flawed irreparably and for several reasons. For one, the stimulus responsible for m…

Differential Diagnosis in Dermatopathology

Discussions

Both angiolymphoid hyperplasia with eosinophilia and angiosarcoma are processes pathologic that involve endothelium-lined blood vessels. Whereas angiolymphoid hyperplasia with eosinophilia is a vascular malformation that comes into being by virtue o…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Verruciform Xanthoma?

“A relationship most likely exists between the verruciform appearance of the epithelium and the underlying foam cells. . . . One might suspect that epithelial breakdown, from some as yet unknown cause may secondarily elicit a foam-cell respo…

Differential Diagnosis in Dermatopathology

Discussions

Both sebaceous hyperplasia and nevus sebaceus of Jadassohn consist of abnormalities of sebaceous glands but the former, as the name denotes, is a hyperplasia, whereas the latter is a hamartoma that involves not only sebaceous units, but other adnexa…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

“Melanoma arising from lentigo maligna is preceded by or forms a part of a recognizable series of events affecting the melanocytic cellular system in a way similar to these stages. First, there is a long period characterized by an increase in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…us, the others being “persistent lentiginous melanocytic hyperplasia,” “atypical melanocytic hyperplasia,” “concentric eosinophilic hyperplasia,” and “lamellar hyperplasia.” We use the designation Clark…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

Objective Although conflicting with the concept of nevi being hamartomas, to date, Spitz and Reed nevi have been regarded as acquired melanocytic nevi, whereas many other types have already been accepted as being congenital. Here, the reader will fi…