Differential Diagnosis in Dermatopathology

Differential Diagnosis

Infundibular cyst Isthmus-catagen cyst 1. Cyst lining consists of stratified squamous epithelium that resembles normal infundibular epidermis, i.e., the cells flatten as they mature; the granular zone persists 1. Cyst lining consists of stratifi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Telogen Effluvium—An Inflammatory Disease?

…ting follicles which have performed the ritual of involution, catagen, in the prescribed [sic] fashion. Inflammatory signs or other histologic abnormalities are necessarily minor or absent or else the follicle could not conclude its growing phase in…

Histologic Diagnosis of Inflammatory Skin Diseases

Telogen effluvium

…psy specimen, at least one and sometimes two follicles are in catagen Correlation clinicopathologic In the first few weeks of the process, the usual complement of follicles still is in anagen, and, therefore, no alopecia is detectable clinically. Ab…

Differential Diagnosis in Dermatopathology

Common baldness vs. Telogen effluvium

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…cognizable clinically results from rupture of an infundibular cyst and the circumstance in which that develops most often is “cystic” acne vulgaris. An abscess centered in an infundibulum is known as a furuncle (Fig. 3.2A), it being cause…

Histologic Diagnosis of Inflammatory Skin Diseases

Alopecia areata, totalis, universalis

…icles often in what seems to be the end of anagen or in early catagen; as a rule, nearly all the follicles are in the same stage of devolution Fully developed Lymphocytes and melanophages at the base of fibrous tracks that represent collapse of per…

Differential Diagnosis in Dermatopathology

Discussions

Infundibulo-folliculo-sebaceous cystic hamartoma and steatocystoma are both cystic hamartomas. Neither is simply a cyst because the structures that comprise each of them are not mere epithelium-lined sacs that house fluid or solid elements, but are…