Histologic Diagnosis of Inflammatory Skin Diseases

Elastic Fibers

…stic fibers are absent from scarring processes such as scars, keloids, and dermatofibromas and are decreased greatly, or are absent altogether, in anetodermas, a feature that accounts in considerable measure for the lax, bulging skin characteristic o…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…negative feedback in proliferation of fibrocytes. Repair of wounds usually is an orderly process, but in some fibrosing dermatitides, such as keloids, fibrocytes escape from regulation and a bulky overgrowth of altered collagen results.  …

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…atients receiving retinoids systemically. Dermatofibromas and keloids are not brought into being by drugs. Panniculitis Erythema nodosum is induced not uncommonly by a drug, but that is not the case for other distinctive patterns of panniculitis such…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tween collagen bundles = Scar, early ¬†As lesions of scars and keloids evolve, fibrocytes not only manufacture collagen, but mucin, seen as granular basophilic material in a section stained by hematoxylin and eosin. 10.96.3A: Fibrosing and vesic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Erythema Dyschromicum Perstans?

…ges histopathologic is not unique. It is true also for scars, keloids, and dermatofibromas, all of which are fibrosing inflammatory processes that examination by conventional microscopy fails almost always to inform about in regard to an inciting cau…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Fibromatoses?

…ould not be applied to reactive fibrous proliferations, or to keloids, which are usually secondary to injury . . .” Burton JL. Disorders of connective tissue. In: Champion RH, Burton JL, Ebling FJG, et al., eds. Textbook of dermatology. 5th ed…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

…er Mosby, 2005:1270. “The histological appearances [of keloids] are typified by a nodular fibroblastic proliferation and the presence of hypocellular, ‘glassy’, eosinophilic, hyalinized collagen fibers in the dermis.” McKee…

Dermatology Practical & Conceptual

Pseudofolliculitis barbae: a dermatoscopic correlate

…dules, or abscesses hyperpigmentation, hypertrophic scars and keloids can also occur [2]. Our patient presented with a solitary inflammatory nodule with no previous history of pseudofolliculitis. Clinical examination was inconclusive. Herein we prese…