Histologic Diagnosis of Inflammatory Skin Diseases

Elastic Fibers

Elastic fibers are synthesized by fibrocytes (Fig. 1.80), those fibers imparting to skin the property of returning to its original shape after the effects of forces that deform it. The fibers are capable of extension to approximately twice their len…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

Neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes are called inflammatory cells because they enter tissue during the process of inflammation. A more exact designation for them is “cells of an inflammatory process”; the…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

Drug eruptions Synonyms Dermatitis medicamentosa Presentation stereotypical Age and sex Any age or either sex, but most common in older persons who take many medications. Immunosuppressed patients, among them those infected with the human immunodefi…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.96.1A: Fibrosing dermatitis + 10.96.1B: Plump fibrocytes, coarse bundles of collagen in haphazard array, and patchy infiltrate of iron-containing macrophages = Scar, very early ¬†Innumerable macrophages replete with iron bear tes…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Erythema Dyschromicum Perstans?

“During the year 1959–1960 in the Department of Dermatology of the Vargas Hospital in Caracas, we studied five adult patients with a peculiar new pigmentary disorder. . . . The skin eruption is characterized by numerous macules with a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Fibromatoses?

“Benign tumors and tumor-like proliferations Fibromatoses Fibroma molle Nonmetastasizing fibrosarcomas Desmoid tumor Keloid Cicatricial fibromatosis Palmar fibromatosis (fibroma or pseudotumor of Dupuytren’s contracture) Plantar fibroma…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Hyalin?

“With the high power the hyaline is seen in very varied forms, which all show the same fuchsin red reaction. The first forms a section by itself; it comprises hyaline balls of different size, which lie free between the epithelial cells, and w…

Dermatology Practical & Conceptual

Pseudofolliculitis barbae: a dermatoscopic correlate

Report of a case A 45-year-old man presented with a slightly tender rash on his face of about three months’ duration. Past medical history was non-contributory. Physical examination revealed a solitary 1 cm erythematous nodule in the right sub…