A Clinical Atlas of 101 Common Skin Diseases

Histiocytosis X

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Differential Diagnosis in Dermatopathology

Pagetoid Bowen’s disease vs. Extramammary Paget’s disease

A proliferation of abnormal Langerhans’ cells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that m…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…osum, there is no granulomatous panniculitis in Behçet”s disease. In some lesions of Behçet”s disease, fibrin is present in the wall of venules and thrombi are found in the lumen of them. Those changes in the deep reticular dermis and sub…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mammary and Extramammary Paget’s Disease?

…ll-Livingstone, 2002. Mammary and extramammary Paget’s disease are rare intraepidermal adenocarcinomas with simialr clincial features that mimic inflammatory or infectous conditions. Whereas mammary Paget’s disease is most often assoica…

Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…may be indistinguishable, too, from one of true Darier’s disease, but ancillary findings nearly always enable specific diagnosis of Grover’s disease to be made. Darier’s disease may display no notable infiltrates of lymphocytes in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Angiolymphoid Hyperplasia with Eosinophilia/Kimura’s Disease?

…perplasia with eosinophilia is a rare benign vasoproliferative disease of unknown cause, which can present as tumour-like nodules in the head and neck. We treated a patient who showed some of the features of Kimura disease (KD), which is an important…