Histologic Diagnosis of Inflammatory Skin Diseases

Images

…10.60.1A: Perivascular dermatitis, interface, focally lichenoid + 10.60.1B: Obscuration of the dermoepidermal junction by lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, and compact orthokeratosis = Lichen planus, early Zone…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.11.1A: Perivascular dermatosis, lichenoid + 11.11.1B: Lymphocytes, many necrotic keratocytes and a subepidermal cleft = Lichen planus-like keratosis, early ┬áBecause lichen planus-like keratosis often is misinterpreted clinically…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent pigmented purpuric dermatitis

…tle purpuric papules may be detectable. Gougerot-Blum’s lichenoid purpura (lichenoid papular variant) consists of minute discrete rust-colored papules; when, in time, the purple gives way to yellow, the condition is known as lichen aureus. Douc…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…persistent pigmented purpuric dermatitides, the others being lichenoid (Gougerot-Blum) and spongiotic (Doucas and Kapetenakis). This pattern, named eponymically for Schamberg, is the most common of three. 10.78.2A: Perivascular dermatitis, lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…sions and ulcers); none of those lesions “erupt.” LICHENOID [L. lichen (skin eruption), Gk. leichen (to lick) + Gk. -oid (in the form of)]: Clinically, flat-topped papules and, histopathologically, a bandlike infiltrate, usually of lympho…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…ous metaplasia) Red man syndrome Serum sickness drug reaction Lichenoid drug reaction Differential diagnosis clinical Only rarely are lichenoid drug eruptions indistinguishable histopathologically from lesions of true lichen planus. As a rule, certa…

Differential Diagnosis in Dermatopathology

Discussions

…histopathologically, among them lichen planus-like keratosis, lichenoid discoid lupus erythematosus, lichenoid photodermatitis, lichenoid secondary syphilis, and lichenoid drug eruptions. Of all the drug eruptions that simulate lichen planus, that in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…Arch Dermatol Syphil 1946;54:472–74. “Keratosis lichenoides chronica is a rare acquired dermatosis of the young adult. Its physiopathology remains elusive. This dermatosis is characterized by keratosic violaceous lichenoid papules distr…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…a-Habermann disease, and secondary syphilis. A psoriasiform lichenoid pattern with abundant plasma cells is a clue to secondary syphilis. The presence of plasma cells and histiocytes in association with what otherwise seems to be findings typical…