Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ld to be those of an early lesion of lichen planus because the lichenoid infiltrate and the epidermal changes are confined to a tiny focus. 10.60.3A: Perivascular dermatitis, interface, lichenoid + 10.60.3B: Lymphocytes only, edema in a der…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…an be observed, along with solar elastosis, at the side of the lichenoid infiltrate. The products of lymphocytes destroy the solar lentigo, the lesion in the process of being decimated then being called lichen planus-like keratosis. The lichenoid inf…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent pigmented purpuric dermatitis

…patients. Miscue clinical as clue to diagnosis histopathologic Lichenoid purpura of Gougerot and Blum misdiagnosed clinically as Kaposi’s sarcoma: Denominators in common: Purpuric papules and plaques are present. Features differentiating: Lich…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…21; 10.78.4A: Perivascular dermatitis, interface, patchy lichenoid + 10.78.4B: Numerous extravasated erythrocytes in combination with an infiltrate of lymphocytes in the upper part of the dermis = Lichenoid purpura of Gougerot-Blum, early  …

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…mostly, in a papillary dermis thickened by it. Nearly always, lichenoid infiltrates of an inflammatory process consist of lymphocytes, as in lichen planus, lichenoid discoid lupus erythematosus, and lichenoid purpura of Gougerot and Blum. Lymphocyte…

Histologic Diagnosis of Inflammatory Skin Diseases

Drug eruptions

…tous metaplasia) Red man syndrome Serum sickness drug reaction Lichenoid drug reaction Differential diagnosis clinical Only rarely are lichenoid drug eruptions indistinguishable histopathologically from lesions of true lichen planus. As a rule, cert…

Differential Diagnosis in Dermatopathology

Discussions

…histopathologically, among them lichen planus-like keratosis, lichenoid discoid lupus erythematosus, lichenoid photodermatitis, lichenoid secondary syphilis, and lichenoid drug eruptions. Of all the drug eruptions that simulate lichen planus, that i…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Keratosis Lichenoides Chronica?

…Arch Dermatol Syphil 1946;54:472–74. “Keratosis lichenoides chronica is a rare acquired dermatosis of the young adult. Its physiopathology remains elusive. This dermatosis is characterized by keratosic violaceous lichenoid papules dist…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…e most common patterns of secondary syphilis are psoriasiform, lichenoid, and psoriasiform lichenoid, and they occur nearly always in conjunction with superficial and deep perivascular infiltrates in which histiocytes and plasma cells, in time, come…