Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

Granuloma faciale Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Localized to the face Shape of lesions Round or oval usually Individual lesions Papules, plaques, nodules, or tumors marked on their surface often…

Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

Miescher’s granuloma of the face Presentation stereotypical Age and sex Women Distribution of lesions Face and scalp Configuration of lesions Annular Individual lesions Plaques Course Resolving after many months Differential diagnosis clinical…

Differential Diagnosis in Dermatopathology

Papular mucinosis vs Interstitial granuloma annulare

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Differential Diagnosis in Dermatopathology

Subcutaneous granuloma annulare vs. Rheumatoid nodule

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Dermatology Practical & Conceptual

Actinic granuloma

Actinic granuloma is a rare, idiopathic disorder of middle-aged adults that always appears in sun-exposed skin [1,2]. It is a form of granulomatous dermatosis characterized by annular plaques with central atrophy and raised erythematous margins that…

Differential Diagnosis in Dermatopathology

Pyogenic granuloma vs. Bacillary angiomatosis

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

Reticulohistiocytic granuloma Synonyms Reticulohistiocytoma Giant cell histiocytoma Presentation stereotypical Age and sex Mostly middle-aged women Distribution of lesions Localized or widespread on the extensor aspect of the hands, forearms, face,…

Differential Diagnosis in Dermatopathology

Granuloma annulare vs. Eruptive xanthoma

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…