Histologic Diagnosis of Inflammatory Skin Diseases

Miescher’s granuloma of the face

…d mechanism Both are unknown. Comment Whether Miescher’s granuloma of the face, a diagnosis made rarely, is a specific disease or a mere variant of granuloma annulare has yet to be determined. The findings are limited to the reticular dermis, w…

Differential Diagnosis in Dermatopathology

Subcutaneous granuloma annulare vs. Rheumatoid nodule

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Dermatology Practical & Conceptual

Actinic granuloma

Actinic granuloma is a rare, idiopathic disorder of middle-aged adults that always appears in sun-exposed skin [1,2]. It is a form of granulomatous dermatosis characterized by annular plaques with central atrophy and raised erythematous margins that…

Differential Diagnosis in Dermatopathology

Pyogenic granuloma vs. Bacillary angiomatosis

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

…ear, binuclear, and multinucleate histiocytes, among which are scattered other types of inflammatory cells. Differential diagnosis histopathologic Xanthogranuloma may be indistinguishable at times from reticulohistiocytic granuloma. In examples stere…

Differential Diagnosis in Dermatopathology

Granuloma annulare vs. Eruptive xanthoma

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Differential Diagnosis in Dermatopathology

Xanthogranuloma vs. Reticulohistiocytic granuloma

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…

Differential Diagnosis in Dermatopathology

Granuloma annulare vs. Necrobiosis lipoidica

A systemic inflammatory process involving venules by deposits of fibrin within their wall in conjunction with neutrophils and nuclear “dust” of neutrophils in the dermis and, at times, the subcutaneous fat. The clinical manifestations ar…