Search Results for: melanocytes

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus?

…blue neuronevus. There is no place for the erroneous concept of nevus cells. The cells that constitute melanocytic nevi are melanocytes and should be called melanocytes. “Naevus, a mark; they are hairy, vascular, or pigmentary.” Fox WT….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nuclear Atypia, Cytoplasmic Atypia, and Architectural Atypia?

…lanocytes have the same features as cytologically atypical cells in any neoplastic system. Such cells are larger than normal melanocytes or the intraepidermal melanocytes of an ordinary melanocytic nevus.” Clark WH Jr., Elder DE, Guerry IV D….

Review of The Pigmentary System: Physiology and Pathophysiology (2nd ed) by James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, et al.

Review of The Pigmentary System: Physiology and Pathophysiology (2nd ed) by James J. Nordlund, Raymond E. Boissy, Vincent J. Hearing, et al.

…analogy with epidermal melanocytes to arise in the neural crest and migrate onto the skin. It has been suggested that dermal melanocytes are simply melanocytes destined for the epidermis that have remained in the dermis. Because of the lack of…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

…not contain melanosomes. Although melanocytes in considerable numbers are interspersed among matrical cells in the bulb, few melanocytes are found along the course of the stem and the isthmus; in the infundibulum, melanocytes are disposed in a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…ouette when formed fully, i.e., compound, symmetrical, well-circumscribed, slightly elevated, and composed of small nests of melanocytes situated at the dermoepidermal junction and in the papillary dermis. It seems simple—and it is! “The…

Melanocytic nevi and melanoma: overlapping criteria—the degree is the key

Melanocytic nevi and melanoma: overlapping criteria—the degree is the key

…igure 2. Melanocytic nevus on the back of a 60 year-old male. (A) (H&E) There are round and elongated confluent nests of melanocytes along with crowded solitary melanocytes with monomorphous small, round-oval nuclei with paltry cytoplasm, at the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

…s III (neoplastic melanocytes filling the papillary dermis and causing the reticular dermis to become bowed), IV (neoplastic melanocytes within the reticular dermis), and V (neoplastic melanocytes in the subcutaneous fat). Changing the names to…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…ry different from those of Clark, to wit, the silhouette of a benign neoplasm, slight elevation, and confinement of nests of melanocytes with small, oval, monomorphous nuclei to the dermoepidermal junction and the papillary dermis. The changes in…