Histologic Diagnosis of Inflammatory Skin Diseases

Blood Vessels

Blood vessels in the skin of an embryo come into being when mesenchymal cells arranged in an intricate network arborize and encircle conduits that are seen through a microscope as mere spaces. The dermal vasculature consists of a superficial and a d…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Origin of Adnexal Neoplasms?

“Thus one needs to bear in mind the information required of a pathologist about a particular tumour, which can be summarized as follows: 1. What is the origin of the tumour? 2. What is likely the behavior of the tumour? 3. What is the extent…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal Papilla?

“Historically, the hair germ has been defined as a group of cells located at the base of the telogen follicle in close contact with the dermal papilla.” Lavker RM, Miller S, Wilson C, et al. Hair follicle stem cells: their location, ro…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine Neoplasms?

Classification of Skin Appendage Tumors Eccrine Differentiation Eccrine nevus Eccrine duct proliferation Eccrine-centered nevus Eccrine angiomatous hamartoma Syringofibroadenoma or acrosyringeal nevus Comedo nevus of the palm, linear eccrine nevu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Psychocutaneous Disorders?

“The influence of the psyche on the skin is greater than on any other organ. It is apparent in the many cutaneous expressions of the emotions, subjective, as well as objective, both in man and in animals. It is for this reason that the skin i…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eruptive Vellus Hair Cyst?

“From the histologic viewpoint, EVHC [eruptive vellus hair cyst] must be differentiated from steatocystoma multiplex.” Gonzalez FU, Cristobal MC, Martinez AA, et al. Eruptive vellus hair cyst with singular histologic finding. Arch Derm…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

“An irreversible alopecia of the scalp occurs in negro women who straighten their hair with hot combs. The disease is common and distinctive, clinically and histopathologically. . . . Hot petrolatum used with the comb causes a chronic inflamm…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Angiolymphoid hyperplasia with eosinophilia Kimura’s disease 1. Does not usually resemble lymphoid tissue when viewed at scanning magnification 1. Resembles lymphoid tissue when viewed at scanning magnification 2. Few lymphoid follicles;…