Search Results for: necrosis

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…1; is intriguing. Does it mean that the vasculitis is accompanied by necrosis of blood vessels or that the vasculitis causes necrosis? Can blood vessels undergo necrosis? Is “necrotizing vasculitis” a distinctive phenomenon or is it…

Histologic Diagnosis of Inflammatory Skin Diseases

Sclerema neonatorum

…obules of the subcutaneous fat Fully developed Needle-shaped clefts in radial array in nearly every adipocyte in fat lobules Necrosis of adipocytes as evidenced by the presence of fat “microcysts” Sparse infiltrate of neutrophils,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ous fat necrosis along the border of fat “microcysts” in company with foam cells in patchy array = Traumatic fat necrosis Membranous fat necrosis, fat “microcysts,” and foam cells are signs that necrosis of adipocytes…

Histologic Diagnosis of Inflammatory Skin Diseases

Pancreatic panniculitis

Pancreatic panniculitis Synonyms Pancreatitis with subcutaneous fat necrosis Systemic nodular fat necrosis Pancreatic enzyme panniculitis Nodular fat necrosis Weber-Christian syndrome of pancreatic origin Presentation stereotypical Age and sex…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wegener’s Granulomatosis?

…of WG [Wegener’s granulomatosis] in the upper and lower respiratory tract are leukocytoclastic vasculitis, parenchymal necrosis, and granulomatous inflammation.” Barksdale SK, Hallahan CW, Kerr GS, et al. Cutaneous pathology in…

Histologic Diagnosis of Inflammatory Skin Diseases

Atypical mycobacterial infections

…ation of acid-fast organisms that are sparse and scattered widely in sections of tissue. If they are to be detected, foci of necrosis and suppuration are the sites on which to concentrate the search. Although halogenodermas can produce changes in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Endothelial Swelling?

…757-62. “The salient features of systemic vasculitis are endothelial swelling, inflammatory infiltrates, and fibrinoid necrosis of the arterial wall. Of these three, the concept of fibrinoid necrosis is undoubtedly the most elusive.”…

Histologic Diagnosis of Inflammatory Skin Diseases

Cold panniculitis

…phages and of spaces known inaccurately as “microcysts.” Differential diagnosis histopathologic Subcutaneous fat necrosis of the newborn is associated with needle-shaped clefts in the cytoplasm of histiocytes especially in fat lobules….

Histologic Diagnosis of Inflammatory Skin Diseases

Hypodermitis sclerodermiformis

…n that membranous and cystic changes in adipose tissue are not specific for any condition, but simply are expressions of fat necrosis, along with granular fat necrosis, foam cells, and deposits of calcium. Some authors emphasized that an…