Search Results for: nerves

Waldenström macroglobulinaemia presenting as tingling ulcers on the feet

Waldenström macroglobulinaemia presenting as tingling ulcers on the feet

…op, develop later. The possible mechanisms in Waldenström macroglobulinaemia include microangiopathy, direct infiltration of nerves, endoneural deposition of IgM protein or amyloidosis, hyperviscosity or immunoglobulin deposit in blood vessels. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Blood Vessels

…ures of adnexa (folliculosebaceous-apocrine units and eccrine units) and nonepithelial structures of adnexa (smooth muscles, nerves, and medium-sized and larger blood vessels). Figure 1.72 The dermal vasculature consists of a network of two plexuses…

Differential Diagnosis in Dermatopathology

Discussions

…uberculoid leprosy is characterized stereotypically by one or several discrete, hypopigmented anesthetic patches. Peripheral nerves may be thickened palpably in patients with that particular form of the disease. Patients with tuberculoid leprosy are…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…;itis (inflammation of)]: A term meant to describe changes in the skin that were thought to be related in some way to “nerves,” either organically or psychologically. Two types of neurodermatitis have been described, namely,…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat

…lomerations of subcutaneous adipocytes into lobules. The fibrous septa also house muscle-containing vessels, lymphatics, and nerves. (x25) Arteries and veins in the subcutaneous fat are positioned within the major fibrous septa (Figs. 1.87 and…

A keratoacanthoma with venous invasion

A keratoacanthoma with venous invasion

…inising tumour and an SCC variant characterised by benign (non-metastasising) behaviour [1]. Although invasion of peripheral nerves has been reported [2,5] this has not been associated with an adverse prognosis. One of the authors (DW, data not…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…xa, i.e., hair follicles, sebaceous units, apocrine units, and eccrine units. Moreover, the vasculature and Schwann cells of nerves also are surrounded by a basement membrane. Figure 1.70 Basement membrane zone as seen through a conventional…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Psychocutaneous Disorders?

…as a consequence of the involuntary pull of smooth muscles on hair follicles in response to powerful emotions? Skin contains nerves that are integral to the peripheral nervous system. As long as mortals think and feel, the effects of those thoughts…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…MA, Parades B, Ackerman AB. Sites of attachment of the muscle of hair erection. Dermatopathol Pract Concept 1995;1:229-233. Nerves Johnson KO. The roles and functions of cutaneous mechanoreceptors. Curr Opin Neurobiol 2001;11:455-461. Johnson KO,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ulosis and hyperkeratosis, it must have been rubbed persistently and forcefully, probably because of effects pruritogenic on nerves of enzymes released from neutrophils. Those effects could be the reason for the implacable pruritus associated with…