Search Results for: neutrophils

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Spongiform Pustular Diseases?

…utrophils are present in the superficial malpighian layers and the stratum corneum. There are subcorneal pustules containing neutrophils and Munro’s microabscesses may be numerous. Neutrophils within the superficial malpighian layer often…

Histologic Diagnosis of Inflammatory Skin Diseases

Behçet’s Disease

…. Those infiltrates, like ones in early lesions of erythema nodosum, consist mostly of lymphocytes, but with a sprinkling of neutrophils. A few neutrophils also are present, in conjunction with lymphocytes, around venules, and are scattered among…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…6.7B: Edema of papillary dermis, lymphocytes along the dermoepidermal junction, spongiosis, pallor across the epidermis, and neutrophils in scale-crusts = Mucha-Habermann disease, acute Neutrophils in mounds of parakeratosis and edema of the…

Histologic Diagnosis of Inflammatory Skin Diseases

The Algorithmic Method

…not equidistant from one another because their nucleus is positioned so eccentrically. Figure 6.4 A&B. Identification of neutrophils at scanning and high magnifications. Neutrophils in this lesion of pyoderma gangrenosum are recognizable at…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…it, the skin. 10.5.11A: Vesicular dermatitis, intraepidermal, spongiotic and ballooned + 10.5.11B: Some eosinophils and many neutrophils in an intraepidermal vesicle = Response to an insect “bite” The finding of so many neutrophils in a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ophils is slight. 10.111.2A: Perivascular and interstitial dermatitis, mixed-cell + 10.111.2B: Lymphocytes, eosinophils, and neutrophils around venules, and neutrophils and eosinophils scattered among collagen bundles in the interstitium of the…

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

…ped Patchy lichenoid infiltrate of lymphocytes mostly, but also of neutrophils and eosinophils Nuclear “dust” of neutrophils accompanies intact neutrophils and the preponderant lymphocytes Mixed-cell infiltrate of lymphocytes,…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…such as the perineum. What makes a lesion of condyloma latum so remarkable from a vantage histopathologic is the surfeit of neutrophils housed in the papillated epidermis. Those neutrophils may be scattered diffusely or they may become aggregated…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

…est of them, is characterized histopathologically by the presence of leukocytoclasis, that is, nuclear “dust” of neutrophils in company with intact neutrophils and, in lesions developed fully, with fibrin in the wall of venules. In…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…isease Thrombi in the lumen of small vessels are evidence of a vasculitis, which is responsible for the ulceration. Although neutrophils and nuclear “dust” of neutrophils are accompaniments often of vasculitis in Behçet’s disease,…