Therapeutic Strategies in Dermatology

Melanoma: Treatment

Treatment Initial therapy First-line therapy: Surgical excision For diagnosis, complete excisional biopsy with minimal margins, pathologically evaluated at multiple levels to determine the tumor thickness, as well as to determine presence of ulcera…

Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

Initial Evaluation Melanoma frequently presents as an asymmetric pigmented lesion with an irregular scalloped border and uneven pigmentation. Some of the lesions are marked by hypopigmented areas (signifying areas of regression) or more darkly pigme…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…s lamellar and concentric is not the province of Clark’s nevi alone, but also of other nevi, e.g., some Spitz’s nevi, and of some melanomas, too. In brief, the finding is not at all helpful in differentiating Clark’s nevus from mela…

Dermatology Practical & Conceptual

Regression of nevi in a melanoma patient treated with interferon

…Israel. Full body skin examination revealed multiple pigmented nevi of the trunk and extremities. Of them, six nevi had a similar dermoscopic pattern, including a network and localized fine and coarse gray granularity which in general represent regre…

A Clinical Atlas of 101 Common Skin Diseases

Verrucae

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

A Clinical Atlas of 101 Common Skin Diseases

Pityriasis Rubra Pilaris

An inflammatory process in which lesions present themselves clinically as red macules and subtle scaly papules. They soon become so confluent that there is widespread redness and scaling punctuated by islands of skin that ostensibly are spared and b…