A Clinical Atlas of 101 Common Skin Diseases

Preface

What prompted the undertaking of this pocket atlas of dermatology? The reasons were several and varied, among them the following: 1.  Pictures are and always have been an extraordinarily valuable vehicle in the study of clinical dermatology. The fir…

A Clinical Atlas of 101 Common Skin Diseases

Pruritic Urticarial Papules and Plaques of Pregnancy

An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition….

Therapeutic Strategies in Dermatology

Impetigo: Initial evaluation

Initial evaluation Impetigo contagiosum Bullous lesions of impetigo Differential diagnosis Herpes simplex: May result in painful or burning, crusted grouped vesicles near the mouth or nares, often recurrent in the…

Therapeutic Strategies in Dermatology

Scabies: Initial Evaluation

Initial Evaluation Erythematous, crusted, excoriated papules, pustules, and vesicles. Linear burrows representing the path of the mite through the skin may also be seen. Wrists, interdigital web spaces, axilla, genitalia are typically affected sites…

Histologic Diagnosis of Inflammatory Skin Diseases

Herpes gestationis

Herpes gestationis Synonyms Pemphigoid gestationis Dermatitis multiformis gestationis Gestational pemphigoid Presentation stereotypical Age and sex Women in the second trimester of pregnancy, but may develop at any stage of gestation Distribution…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Acquired Epidermolysis Bullosa?

…differentiation of acquired epidermolysis bullosa from bullous pemphigoid, because binding of basement-membrane immunoglobulins and complement in vivo already was known to occur in bullous pemphigoid and in some other disorders of the skin, such as d…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ous papillary dermis and in the acanthotic epidermis = Bullous pemphigoid, urticarial Eosinophils in the epidermis induce spongiosis that, at times, leads to formation of spongiotic vesicles. Uncommonly, a blister in bullous pemphigoid is entirely in…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vesicular Dermatitis

…, so, too, it is for eosinophils in dermal papillae of bullous pemphigoid and herpes gestationis. Episodically, a subepidermal blister of bullous pemphigoid is laden with neutrophils (Fig. 5.286 A&B), and one of dermatitis herpetiformis is filled…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal and Epidermal Types of Erythema Multiforme?

…of that time, when they submitted biopsy specimens of bullous pemphigoid to laboratories of dermatopathology and of general pathology, continued to employ the old term chronic bullous erythema multiforme for what really was bullous pemphigoid. Histo…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermoepithelial Interface

…emidesmosomes. Proteins in hemidesmosomes are plectin, bullous pemphigoid antigen 1 (BPAg1), bullous pemphigoid antigen 2 (BPAg2), integrin subunit α6, and integrin subunit β4. Destruction of hemidesmosomes leads inevitably to development of a subepi…