Histologic Diagnosis of Inflammatory Skin Diseases

Images

…, and cornified cells, as well as neutrophils of a suppurative infundibulitis are sent flying into the dermis on rupture of the infundibulum, the result being suppurative peri-infundibulitis in addition to infundibulitis. Microorganisms found outside…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…s are but a few days old. Figure 5.310 A&B. Suppurative infundibulitis, not suppurative folliculitis! Neutrophils present to overflowing in an infundibulum qualifies as suppurative infundibulitis, not as suppurative folliculitis, the infundibu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…inflammation indicates that the process began as a suppurative infundibulitis. Not surprisingly, pustules are a finding common clinical in rosacea. 10.94.3A: Infundibulitis, suppurative, and peri-infundibulitis, granulomatous + 10.94.3B: Hi…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ulitis must be distinguished from the inordinately more common perivasculitides and peri-infundibulitides/folliculitides. In the latter circumstances, there are neither fibrin in the wall nor thrombi within the lumen of vessels. The most common vascu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ed dermal papillae and compact orthokeratosis. 10.60.7A: Perivascular dermatitis and peri-infundibulitis, lichenoid + 10.60.7B: Patchy infiltrates of lymphocytes seated beneath thickened, hypergranolotic infundibula = Lichen planus, hypertr…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…e fundamental patterns were set forth as follows: Superficial perivascular dermatitis (Fig. 5.6A) Superficial and deep perivascular dermatitis (Fig. 5.6B) Nodular and diffuse dermatitis (Fig. 5.6C) Vasculitis (Fig. 5.6D) Intraepidermal vesicular and…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tis or perifolliculitis, as illustrated here. 10.22.12A: Perifolliculitis, mixed-cell + 10.22.12B: Hyphae in a hair and an inner sheath = Dermatophytosis The presence of perifolliculitis, even in the absence of suppurative infundibulitis, s…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…id lupus erythematosus and in dermatomyositis. 10.63.7A: Perivascular dermatitis, interface, vacuolar and peri-infundibulitis/perifolliculitis + 10.63.7B: Lymphocytes, telangiectases, mucin in the upper part of the dermis, thickened basemen…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…ly signs of prurigo nodularis or picker’s nodule. Error: Perioral and periocular dermatitis are something other than rosacea. Reason: What are called perioral and periocular dermatitis are papular expressions of rosacea, just as is lupus miliar…

Differential Diagnosis in Dermatopathology

Acne vulgaris, erythematous papule vs. Rosacea, erythematous papule

An inflammatory process that often begins as a suppurative folliculitis manifested clinically as pustules. It rapidly extends to become ulcers marked at their periphery by boggy tissue. The skin disease is associated commonly with inflammatory bowel…