Histologic Diagnosis of Inflammatory Skin Diseases

Images

…and cornified cells, as well as neutrophils of a suppurative infundibulitis are sent flying into the dermis on rupture of the infundibulum, the result being suppurative peri-infundibulitis in addition to infundibulitis. Microorganisms found outside…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…nfundibular cyst) (Fig. 5.315 A&B). Not every suppurative infundibulitis progresses invariably to granulomatous and fibrosing peri-infundibulitis, although in explosive examples of the process, such as in some patients with conglobata acne, that…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.94.1A: Infundibulitis, spongiotic, and peri-infundibulitis, granulomatous + 10.94.1B: Lymphocytes and plasma cells around collections of epithelioid histiocytes = Rosacea, papular ┬áSpongiosis in an infundibulum is a finding comm…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…o be relatively early because it is so small. 10.60.6A: Peri-infundibulitis, lichenoid + 10.60.6B: Infiltrate of lymphocytes in an arc at the base of a thickened, hypergranulotic infundibulum associated with compact orthokeratosis = Lichen…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…that is, epithelium of the isthmus, stem, and bulb. See also INFUNDIBULITIS/PERI-INFUNDIBULITIS. GRANULATION TISSUE [L. granulum (granule) + -onis (forming) + textere (to weave)]: Highly vascular edematous connective tissue laced with a mixture of i…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…consequence of progression downward of fulminant suppurative infundibulitis as happens in acne conglobata, perifolliculitis abscedens et suffodiens, and hidradenitis suppurativa. In the new schema employed here, what was referred to previously as &#…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…is or perifolliculitis, as illustrated here. 10.22.12A: Perifolliculitis, mixed-cell + 10.22.12B: Hyphae in a hair and an inner sheath = Dermatophytosis The presence of perifolliculitis, even in the absence of suppurative infundibulitis, sh…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…d lupus erythematosus and in dermatomyositis. 10.63.7A: Perivascular dermatitis, interface, vacuolar and peri-infundibulitis/perifolliculitis + 10.63.7B: Lymphocytes, telangiectases, mucin in the upper part of the dermis, thickened basement…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…an inflammatory disease. Reason: Traction induces a lichenoid peri-infundibulitis (and, sometimes, perifolliculitis, especially of the isthmus) composed mostly of lymphocytes and eventuates in peri-infundibular (and sometimes perifollicular) fibropla…

Differential Diagnosis in Dermatopathology

Acne vulgaris, erythematous papule vs. Rosacea, erythematous papule

…pustules. It rapidly extends to become ulcers marked at their periphery by boggy tissue. The skin disease is associated commonly with inflammatory bowel disease, especially ulcerative colitis, and sometimes with rheumatoid arthritis, paraproteinemia,…