Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Junctional Activity and Active Junctional Nevus?

…onal activity ceases and the lesion is composed only of dermal nevus cells (intradermal nevus).” Weedon D. Lentigines, nevi, and melanomas. In: Skin Pathology. 2nd ed. New York, NY: Churchill-Livingstone, 2002:806. “Intradermal nevi sho…

Clinical Case Studies

Nevus of Ota

…he left infraorbital region. There was no associated change in skin texture. No scleral pigment was noted. Figure 1. Nevus of Ota at patient’s initial presentation. Nevus of Ota was suspected because of the history and morphology. Nevus of O…

Differential Diagnosis in Dermatopathology

Dermatofibroma vs. Desmoplastic Spitz’s nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Spitz’s nevus, compound type vs. Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Nevus verrucosus vs. Acanthosis nigricans

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Differential Diagnosis in Dermatopathology

Sebaceous hyperplasia vs. Nevus sebaceus of Jadassohn

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…